C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenergic receptor, alpha 2c
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000049545 Adra2c-201 ENSMUSG00000045318 10090 + 5:35278566-35281761 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049545
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049545 0.540±0.24 0.705±0.33 0.236±0.00 4.077±4.08 0.186±0.09 0.750±0.07 0.189±0.05 1.006±0.11 0.014±0.01 0.039±0.01 0.171±0.04 2.858±1.21 0.525±0.37 0.092±0.06

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 IDA G-protein coupled receptor activity
GO:0004938 TAS alpha2-adrenergic receptor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005887 IEA integral component of plasma membrane
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007565 IEA female pregnancy
GO:0030168 IEA platelet activation
GO:0030424 IEA axon
GO:0031694 IEA alpha-2A adrenergic receptor binding
GO:0032148 IEA activation of protein kinase B activity
GO:0035625 IEA epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
GO:0042803 IEA protein homodimerization activity
GO:0043679 IEA axon terminus
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045907 IEA positive regulation of vasoconstriction
GO:0046982 IEA protein heterodimerization activity
GO:0051379 IEA epinephrine binding
GO:0051930 IEA regulation of sensory perception of pain
GO:0070473 IEA negative regulation of uterine smooth muscle contraction
GO:0071883 IEA activation of MAPK activity by adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000101562 adra2c-001 protein_coding Danio_rerio 0 230
ENST00000280155 ADRA2A-001 protein_coding Homo_sapiens 0 385
ENST00000330055 ADRA2C-002 protein_coding Homo_sapiens 0 1838
ENST00000509482 ADRA2C-001 protein_coding Homo_sapiens 0 1391
ENST00000620793 ADRA2B-001 protein_coding Homo_sapiens 0 331

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