C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cell division cycle 42
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000051477 Cdc42-001 ENSMUSG00000006699 10090 - 4:137319696-137357720 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000051477
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000051477 105.149±2.47 40.949±3.47 145.719±7.65 60.857±32.36 81.379±22.46 49.126±5.59 38.159±1.46 61.840±13.31 61.981±29.01 92.992±9.08 52.557±2.72 49.137±18.24 102.139±60.75 17.665±7.61

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0002040 IEA sprouting angiogenesis
GO:0003161 IGI cardiac conduction system development
GO:0003334 IMP keratinocyte development
GO:0003924 TAS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IDA GTP binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005925 IEA focal adhesion
GO:0006184 TAS GTP catabolic process
GO:0007015 IEA actin filament organization
GO:0007030 IEA Golgi organization
GO:0007088 IMP regulation of mitosis
GO:0007097 IMP nuclear migration
GO:0007163 TAS establishment or maintenance of cell polarity
GO:0007266 TAS Rho protein signal transduction
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0016020 ISS membrane
GO:0016197 TAS endosomal transport
GO:0016337 TAS single organismal cell-cell adhesion
GO:0019901 IPI protein kinase binding
GO:0021762 IEA substantia nigra development
GO:0030036 IEA actin cytoskeleton organization
GO:0030141 IEA secretory granule
GO:0030175 IEA filopodium
GO:0030496 ISS midbody
GO:0030742 IPI GTP-dependent protein binding
GO:0031069 IMP hair follicle morphogenesis
GO:0031256 IDA leading edge membrane
GO:0031274 IEA positive regulation of pseudopodium assembly
GO:0031333 IEA negative regulation of protein complex assembly
GO:0031424 IMP keratinization
GO:0031435 IEA mitogen-activated protein kinase kinase kinase binding
GO:0031647 IMP regulation of protein stability
GO:0031996 IEA thioesterase binding
GO:0032467 ISS positive regulation of cytokinesis
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0034191 IEA apolipoprotein A-I receptor binding
GO:0034332 IMP adherens junction organization
GO:0034613 IMP cellular protein localization
GO:0035088 IMP establishment or maintenance of apical/basal cell polarity
GO:0035264 IMP multicellular organism growth
GO:0036336 IGI dendritic cell migration
GO:0036464 IEA cytoplasmic ribonucleoprotein granule
GO:0042176 IMP regulation of protein catabolic process
GO:0042802 IEA identical protein binding
GO:0042995 IDA cell projection
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043410 IDA positive regulation of MAPK cascade
GO:0043497 IDA regulation of protein heterodimerization activity
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0043552 IMP positive regulation of phosphatidylinositol 3-kinase activity
GO:0045177 IDA apical part of cell
GO:0045740 IEA positive regulation of DNA replication
GO:0045859 IMP regulation of protein kinase activity
GO:0046330 IEA positive regulation of JNK cascade
GO:0046847 IDA filopodium assembly
GO:0048554 IEA positive regulation of metalloenzyme activity
GO:0048664 IMP neuron fate determination
GO:0048730 IMP epidermis morphogenesis
GO:0051017 IMP actin filament bundle assembly
GO:0051233 ISS spindle midzone
GO:0051246 IMP regulation of protein metabolic process
GO:0051489 ISS regulation of filopodium assembly
GO:0051647 IMP nucleus localization
GO:0051683 IEA establishment of Golgi localization
GO:0051835 IEA positive regulation of synapse structural plasticity
GO:0051988 ISS regulation of attachment of spindle microtubules to kinetochore
GO:0060047 IGI heart contraction
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060661 IEA submandibular salivary gland formation
GO:0060684 IMP epithelial-mesenchymal cell signaling
GO:0060789 IMP hair follicle placode formation
GO:0070062 IEA extracellular vesicular exosome
GO:0071338 IMP positive regulation of hair follicle cell proliferation
GO:0071944 IDA cell periphery
GO:0072384 IEA organelle transport along microtubule
GO:0072686 ISS mitotic spindle
GO:0090135 IEA actin filament branching
GO:0090136 IMP epithelial cell-cell adhesion
GO:0090316 IEA positive regulation of intracellular protein transport
GO:1900026 ISS positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000142546 cdc42l2-001 protein_coding Danio_rerio 6e-33 147
ENST00000315554 CDC42-002 protein_coding Homo_sapiens 0 957
ENST00000344548 CDC42-001 protein_coding Homo_sapiens 0 1917
ENST00000400259 CDC42-201 protein_coding Homo_sapiens 0 1881
ENST00000411827 CDC42-004 protein_coding Homo_sapiens 0 725
ENST00000420654 RP11-419M24.5-001 processed_pseudogene Homo_sapiens 0 418
ENST00000421246 CDC42P6-001 processed_pseudogene Homo_sapiens 0 909
ENST00000448566 CDC42P2-001 processed_pseudogene Homo_sapiens 0 752
ENST00000456658 CDC42P1-001 processed_pseudogene Homo_sapiens 0 579
ENST00000498236 CDC42-003 processed_transcript Homo_sapiens 0 654
ENST00000510507 CDC42P4-001 processed_pseudogene Homo_sapiens 0 525
ENST00000518493 CDC42P3-001 processed_pseudogene Homo_sapiens 0 859
ENST00000518654 CDC42P5-001 processed_pseudogene Homo_sapiens 0 708

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