C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263025 MAPK3-001 ENSG00000102882 9606 - 16:30114105-30123294 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungOvaryPlacentaTestisENST00000263025
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000263025 54.358±0.00 41.133±0.00 0.316±0.00 53.852±0.00 21.667±20.64 20.351±19.55 9.400±0.00 14.783±0.00 67.920±0.00 54.705±6.95 82.142±29.00 39.333±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA:NAS MAPK cascade
GO:0000186 TAS activation of MAPKK activity
GO:0000187 TAS activation of MAPK activity
GO:0001784 IEA phosphotyrosine binding
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 IEA protein kinase activity
GO:0004707 IEA:NAS MAP kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005769 TAS early endosome
GO:0005770 TAS late endosome
GO:0005794 TAS Golgi apparatus
GO:0005829 TAS cytosol
GO:0005856 TAS cytoskeleton
GO:0005901 TAS caveola
GO:0005925 TAS focal adhesion
GO:0006351 IEA transcription, DNA-templated
GO:0006360 TAS transcription from RNA polymerase I promoter
GO:0006361 TAS transcription initiation from RNA polymerase I promoter
GO:0006468 IDA:IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0006975 IDA DNA damage induced protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009887 IEA organ morphogenesis
GO:0010467 TAS gene expression
GO:0015630 IDA microtubule cytoskeleton
GO:0016032 IEA viral process
GO:0016310 IDA phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019233 IEA sensory perception of pain
GO:0019902 IPI phosphatase binding
GO:0030168 TAS platelet activation
GO:0030509 IMP BMP signaling pathway
GO:0031143 IEA pseudopodium
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032496 IEA response to lipopolysaccharide
GO:0032872 TAS regulation of stress-activated MAPK cascade
GO:0033129 IMP positive regulation of histone phosphorylation
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035066 IMP positive regulation of histone acetylation
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038083 IDA peptidyl-tyrosine autophosphorylation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043330 IEA response to exogenous dsRNA
GO:0045087 TAS innate immune response
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051090 TAS regulation of sequence-specific DNA binding transcription factor activity
GO:0051216 IEA cartilage development
GO:0051403 TAS stress-activated MAPK cascade
GO:0051493 TAS regulation of cytoskeleton organization
GO:0060397 TAS JAK-STAT cascade involved in growth hormone signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0070498 IMP interleukin-1-mediated signaling pathway
GO:0070849 IDA response to epidermal growth factor
GO:0071260 IEP cellular response to mechanical stimulus
GO:0072584 TAS caveolin-mediated endocytosis
GO:0090170 TAS regulation of Golgi inheritance
GO:2000641 TAS regulation of early endosome to late endosome transport
GO:2000657 IEA negative regulation of apolipoprotein binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000057669 Mapk3-001 protein_coding Mus_musculus 0 1578
ENSMUST00000050201 Mapk3-003 protein_coding Mus_musculus 0 1351
ENSMUST00000091328 Mapk3-002 protein_coding Mus_musculus 0 1339
ENSDART00000103746 mapk3-001 protein_coding Danio_rerio 0 763
ENSDART00000149700 mapk1-002 protein_coding Danio_rerio 0 647
ENSDART00000030213 mapk1-001 protein_coding Danio_rerio 0 647
ENSMUST00000135649 Mapk3-005 processed_transcript Mus_musculus 0 490
ENSMUST00000120966 Gm7746-001 processed_pseudogene Mus_musculus 0 470
ENSDART00000047248 nlk2-201 protein_coding Danio_rerio 0.00000002 66
ENSDART00000123937 nlk2-001 protein_coding Danio_rerio 0.00000002 66

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