C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin induced gene 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000059155 Insig1-001 ENSMUSG00000045294 10090 + 5:28071363-28078662 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000059155
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000059155 170.147±68.18 375.252±17.90 20.063±4.59 20.098±7.20 195.178±86.67 60.444±16.08 8.955±0.84 32.102±4.33 155.308±107.23 56.134±15.56 3.999±0.63 58.505±27.00 20.351±17.32 6.733±2.73

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00026E CIL_00026E_0002 CGP 5:27841947-28078662
CIL_0008KT CIL_0008KT_0002 VISTA 5:27878923-28480422

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005783 TAS endoplasmic reticulum
GO:0006641 IGI triglyceride metabolic process
GO:0006695 IGI cholesterol biosynthetic process
GO:0006991 IDA response to sterol depletion
GO:0008203 IGI cholesterol metabolic process
GO:0010894 IGI negative regulation of steroid biosynthetic process
GO:0016126 IGI sterol biosynthetic process
GO:0032933 IEA SREBP signaling pathway
GO:0032937 IEA SREBP-SCAP-Insig complex
GO:0042472 IGI inner ear morphogenesis
GO:0042474 IGI middle ear morphogenesis
GO:0045599 IDA negative regulation of fat cell differentiation
GO:0045717 IGI negative regulation of fatty acid biosynthetic process
GO:0060021 IGI palate development
GO:0060363 IGI cranial suture morphogenesis
GO:1901303 IEA negative regulation of cargo loading into COPII-coated vesicle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000340368 INSIG1-001 protein_coding Homo_sapiens 0 867
ENST00000342407 INSIG1-003 protein_coding Homo_sapiens 0 313
ENST00000344756 INSIG1-201 protein_coding Homo_sapiens 0 377
ENST00000425172 INSIG1-002 protein_coding Homo_sapiens 6e-38 161
ENST00000468307 INSIG1-004 retained_intron Homo_sapiens 0 320
ENST00000476756 INSIG1-005 protein_coding Homo_sapiens 0 664

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