C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: mitogen-activated protein kinase kinase 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000062686 Map2k7-002 ENSMUSG00000002948 10090 + 8:4238761-4247897 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000062686
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000062686 13.511±3.21 13.079±1.10 10.050±0.17 11.480±4.02 5.687±1.60 14.268±1.44 4.714±1.53 3.578±1.04 12.320±1.77 25.093±0.87 14.445±2.49 3.294±1.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002FU CIL_0002FU_0002 CGP 8:4226827-4251423
CIL_0002FR CIL_0002FR_0002 CGP 8:4238740-4251423

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 IDA MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006915 IEA apoptotic process
GO:0006950 IDA response to stress
GO:0007257 IDA activation of JUN kinase activity
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019903 IPI protein phosphatase binding
GO:0051403 IDA stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000397979 MAP2K7-002 protein_coding Homo_sapiens 0 1589
ENST00000397981 MAP2K7-001 protein_coding Homo_sapiens 0 1496
ENST00000397983 MAP2K7-003 protein_coding Homo_sapiens 0 1930
ENST00000468058 MAP2K7-004 retained_intron Homo_sapiens 0 1275
ENST00000475022 MAP2K7-005 retained_intron Homo_sapiens 0.00000000000003 84
ENST00000494348 MAP2K7-008 retained_intron Homo_sapiens 0 222

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