C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000397983 MAP2K7-003 ENSG00000076984 9606 + 19:7903885-7914459 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000397983
Transcript ID Adipose Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000397983 6.195±0.00 0.344±0.00 4.804±0.00 6.690±0.00 7.623±0.00 9.088±0.00 2.004±1.25 3.059±2.85 15.270±14.86 9.802±1.24 6.863±1.91 7.672±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002FU CIL_0002FU_0001 CGP 19:7888505-7914478
CIL_0002FR CIL_0002FR_0001 CGP 19:7903843-7919097

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 IDA MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0006950 IEA response to stress
GO:0006970 IDA response to osmotic stress
GO:0007165 TAS signal transduction
GO:0007254 TAS JNK cascade
GO:0007257 ISS activation of JUN kinase activity
GO:0008022 IEA protein C-terminus binding
GO:0008545 IEA JUN kinase kinase activity
GO:0009408 IDA response to heat
GO:0009411 IDA response to UV
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0019903 ISS protein phosphatase binding
GO:0031435 IEA mitogen-activated protein kinase kinase kinase binding
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0034612 IDA response to tumor necrosis factor
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045087 TAS innate immune response
GO:0051403 IDA stress-activated MAPK cascade
GO:0072709 IEA cellular response to sorbitol

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000062686 Map2k7-002 protein_coding Mus_musculus 0 1930
ENSMUST00000003027 Map2k7-003 protein_coding Mus_musculus 0 1801
ENSMUST00000145165 Map2k7-005 nonsense_mediated_decay Mus_musculus 0 1788
ENSMUST00000110994 Map2k7-006 protein_coding Mus_musculus 0 1592
ENSMUST00000110998 Map2k7-001 protein_coding Mus_musculus 0 1589
ENSMUST00000110996 Map2k7-008 protein_coding Mus_musculus 0 1474
ENSMUST00000110995 Map2k7-007 protein_coding Mus_musculus 0 1463
ENSMUST00000110999 Map2k7-004 protein_coding Mus_musculus 0 1459
ENSMUST00000129537 Map2k7-010 retained_intron Mus_musculus 0 675
ENSMUST00000129866 Map2k7-009 processed_transcript Mus_musculus 0 366

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