C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: msh homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000063116 Msx1-001 ENSMUSG00000048450 10090 - 5:37820485-37824583 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000063116
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000063116 21.255±19.40 1.966±0.26 1.661±0.20 3.930±1.42 6.951±0.68 0.283±0.08 1.591±0.25 0.487±0.07 0.071±0.05 2.490±0.19 0.968±0.34 10.774±5.02 0.676±0.49 0.051±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000967 CIL_000967_0002 VISTA 5:37518652-38119645
CIL_0008Y0 CIL_0008Y0_0002 VISTA 5:37525669-38129220
CIL_0008DJ CIL_0008DJ_0002 VISTA 5:37551391-38152218
CIL_000969 CIL_000969_0002 VISTA 5:37601106-38202493
CIL_00096C CIL_00096C_0002 VISTA 5:37617742-38218594
CIL_00096B CIL_00096B_0002 VISTA 5:37667623-38269196
CIL_0008QQ CIL_0008QQ_0002 VISTA 5:37760247-38361421
CIL_00096M CIL_00096M_0002 VISTA 5:37765055-38366694
CIL_0008ZA CIL_0008ZA_0002 VISTA 5:37806142-38406996

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IEA cell morphogenesis
GO:0000977 IMP RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000982 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0001227 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001701 IMP in utero embryonic development
GO:0001837 IMP epithelial to mesenchymal transition
GO:0002039 IEA p53 binding
GO:0003007 IGI heart morphogenesis
GO:0003198 IGI epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003677 IDA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IGI nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007507 IGI heart development
GO:0007517 IPI muscle organ development
GO:0008285 IGI negative regulation of cell proliferation
GO:0009952 IGI anterior/posterior pattern specification
GO:0010463 IMP mesenchymal cell proliferation
GO:0021983 IEA pituitary gland development
GO:0023019 IGI signal transduction involved in regulation of gene expression
GO:0030308 IEA negative regulation of cell growth
GO:0030326 IGI embryonic limb morphogenesis
GO:0030509 IGI BMP signaling pathway
GO:0030513 IGI positive regulation of BMP signaling pathway
GO:0030900 IMP forebrain development
GO:0030901 IMP midbrain development
GO:0034504 IEA protein localization to nucleus
GO:0035115 IGI embryonic forelimb morphogenesis
GO:0035116 IGI embryonic hindlimb morphogenesis
GO:0035880 IMP embryonic nail plate morphogenesis
GO:0042474 IMP middle ear morphogenesis
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0042476 IMP odontogenesis
GO:0042481 IGI regulation of odontogenesis
GO:0042733 IGI embryonic digit morphogenesis
GO:0043066 IGI negative regulation of apoptotic process
GO:0043392 IDA negative regulation of DNA binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048863 IGI stem cell differentiation
GO:0050821 IEA protein stabilization
GO:0051154 IDA negative regulation of striated muscle cell differentiation
GO:0051216 IEA cartilage development
GO:0060021 IMP palate development
GO:0060325 IMP face morphogenesis
GO:0060349 IMP bone morphogenesis
GO:0060536 IMP cartilage morphogenesis
GO:0061180 IGI mammary gland epithelium development
GO:0061312 IGI BMP signaling pathway involved in heart development
GO:0071316 IEA cellular response to nicotine
GO:0090427 IGI activation of meiosis
GO:1902255 IEA positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO:2000678 IGI negative regulation of transcription regulatory region DNA binding
GO:2001055 IGI positive regulation of mesenchymal cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000382723 MSX1-001 protein_coding Homo_sapiens 0 1188
ENST00000468421 MSX1-002 processed_transcript Homo_sapiens 0 392

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