C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: angiotensin II receptor, type 1a
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000066412 Agtr1a-001 ENSMUSG00000049115 10090 + 13:30336441-30382867 protein_coding

Mus musculus EnsemblGRCm38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066412
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066412 11.891±1.14 108.581±3.88 2.892±0.38 0.268±0.17 20.591±3.79 4.708±0.79 20.590±3.75 41.357±6.47 35.752±23.84 13.756±0.95 1.024±0.20 3.540±1.62 2.604±3.04 13.290±7.46

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001568 IGI blood vessel development
GO:0001596 IDA angiotensin type I receptor activity
GO:0001822 IMP kidney development
GO:0001921 IEA positive regulation of receptor recycling
GO:0001965 IEA G-protein alpha-subunit binding
GO:0001991 IGI regulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0002001 IMP renin secretion into blood stream
GO:0002018 IMP renin-angiotensin regulation of aldosterone production
GO:0002019 IMP regulation of renal output by angiotensin
GO:0002035 IMP brain renin-angiotensin system
GO:0004945 IEA angiotensin type II receptor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IDA endosome
GO:0005794 IEA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006885 IEA regulation of pH
GO:0006954 IGI inflammatory response
GO:0007186 IC G-protein coupled receptor signaling pathway
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007507 IMP heart development
GO:0007568 IEA aging
GO:0008284 IMP positive regulation of cell proliferation
GO:0012505 IEA endomembrane system
GO:0012506 IEA vesicle membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0017046 IEA peptide hormone binding
GO:0019229 IEA regulation of vasoconstriction
GO:0019901 IEA protein kinase binding
GO:0030425 IEA dendrite
GO:0031410 IEA cytoplasmic vesicle
GO:0031748 IEA D1 dopamine receptor binding
GO:0031968 IEA organelle outer membrane
GO:0031983 IEA vesicle lumen
GO:0032930 IEA positive regulation of superoxide anion generation
GO:0034391 IGI regulation of smooth muscle cell apoptotic process
GO:0034392 IMP negative regulation of smooth muscle cell apoptotic process
GO:0042310 IEA vasoconstriction
GO:0042416 IEA dopamine biosynthetic process
GO:0042756 IGI drinking behavior
GO:0042976 IEA activation of Janus kinase activity
GO:0043621 IEA protein self-association
GO:0043627 IEA response to estrogen
GO:0045777 IDA positive regulation of blood pressure
GO:0050715 IMP positive regulation of cytokine secretion
GO:0055037 IEA recycling endosome
GO:0071549 IEA cellular response to dexamethasone stimulus
GO:0086097 IEA phospholipase C-activating angiotensin-activated signaling pathway
GO:0090190 IEA positive regulation of branching involved in ureteric bud morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000349243 AGTR1-001 protein_coding Homo_sapiens 0 1256
ENST00000402260 AGTR1-201 protein_coding Homo_sapiens 0 1238
ENST00000404754 AGTR1-003 protein_coding Homo_sapiens 0 1238
ENST00000418473 AGTR1-202 protein_coding Homo_sapiens 0 1238
ENST00000461609 AGTR1-007 protein_coding Homo_sapiens 0 1238
ENST00000474935 AGTR1-006 protein_coding Homo_sapiens 0 1238
ENST00000475347 AGTR1-005 protein_coding Homo_sapiens 0 1238
ENST00000497524 AGTR1-002 protein_coding Homo_sapiens 0 1238

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