C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: angiotensin II receptor, type 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000475347 AGTR1-005 ENSG00000144891 9606 + 3:148730100-148742247 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyENST00000475347
Transcript ID Kidney
ENST00000475347 2.218±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001558 NAS regulation of cell growth
GO:0001596 IDA angiotensin type I receptor activity
GO:0001822 IMP kidney development
GO:0002018 NAS renin-angiotensin regulation of aldosterone production
GO:0002034 IC regulation of blood vessel size by renin-angiotensin
GO:0003081 IC regulation of systemic arterial blood pressure by renin-angiotensin
GO:0004930 IEA G-protein coupled receptor activity
GO:0004945 IDA angiotensin type II receptor activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0007186 IDA:IEA G-protein coupled receptor signaling pathway
GO:0007200 NAS phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007266 IDA Rho protein signal transduction
GO:0010744 IC positive regulation of macrophage derived foam cell differentiation
GO:0010873 IMP positive regulation of cholesterol esterification
GO:0016021 NAS:IEA integral component of membrane
GO:0019229 IC regulation of vasoconstriction
GO:0019722 IDA calcium-mediated signaling
GO:0031711 IPI bradykinin receptor binding
GO:0032270 IMP positive regulation of cellular protein metabolic process
GO:0032430 IMP positive regulation of phospholipase A2 activity
GO:0033864 TAS positive regulation of NAD(P)H oxidase activity
GO:0034374 NAS low-density lipoprotein particle remodeling
GO:0035813 NAS regulation of renal sodium excretion
GO:0038166 IDA angiotensin-activated signaling pathway
GO:0042127 NAS regulation of cell proliferation
GO:0042312 IC regulation of vasodilation
GO:0046982 IPI protein heterodimerization activity
GO:0050727 IC regulation of inflammatory response
GO:0050729 TAS positive regulation of inflammatory response
GO:0051482 IDA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0060326 IDA cell chemotaxis
GO:0086097 IDA phospholipase C-activating angiotensin-activated signaling pathway
GO:2000379 TAS positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000066412 Agtr1a-001 protein_coding Mus_musculus 0 1238
ENSMUST00000163776 Agtr1b-201 protein_coding Mus_musculus 0 1142
ENSMUST00000068316 Agtr1b-001 protein_coding Mus_musculus 0 1142

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