C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: a disintegrin and metallopeptidase domain 10
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000067880 Adam10-001 ENSMUSG00000054693 10090 + 9:70678997-70780229 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067880
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067880 12.036±3.61 4.135±0.93 25.178±0.63 12.746±4.79 13.686±2.89 9.509±2.76 5.479±0.23 9.497±0.84 17.760±16.28 14.447±1.63 3.148±0.57 12.325±6.81 27.698±6.18 2.777±1.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MN CIL_0008MN_0002 VISTA 9:70534536-71135234
CIL_0004P1 CIL_0004P1_0002 CGP 9:70678997-70934808

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0004175 IDA endopeptidase activity
GO:0004222 ISS metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 ISS Golgi apparatus
GO:0005798 ISS Golgi-associated vesicle
GO:0005886 TAS plasma membrane
GO:0005925 IEA focal adhesion
GO:0006468 IDA protein phosphorylation
GO:0006509 ISS membrane protein ectodomain proteolysis
GO:0006913 NAS nucleocytoplasmic transport
GO:0007162 ISS negative regulation of cell adhesion
GO:0007219 IMP Notch signaling pathway
GO:0007220 NAS Notch receptor processing
GO:0008237 IMP metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0009986 ISS cell surface
GO:0010820 IEA positive regulation of T cell chemotaxis
GO:0014069 IDA postsynaptic density
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0017124 IEA SH3 domain binding
GO:0019901 IDA protein kinase binding
GO:0030307 IEA positive regulation of cell growth
GO:0030335 IEA positive regulation of cell migration
GO:0034612 IEA response to tumor necrosis factor
GO:0042117 IEA monocyte activation
GO:0042169 NAS SH2 domain binding
GO:0042803 IPI protein homodimerization activity
GO:0051088 IEA PMA-inducible membrane protein ectodomain proteolysis
GO:0051089 IEA constitutive protein ectodomain proteolysis
GO:0070062 IEA extracellular vesicular exosome
GO:0097038 IEA perinuclear endoplasmic reticulum
GO:0097197 IEA tetraspanin-enriched microdomain

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000099639 adam10a-001 protein_coding Danio_rerio 0 270
ENST00000260408 ADAM10-001 protein_coding Homo_sapiens 0 5485
ENST00000396136 ADAM10-002 nonsense_mediated_decay Homo_sapiens 0 2785
ENST00000402627 ADAM10-006 protein_coding Homo_sapiens 0 952
ENST00000439637 ADAM10-010 protein_coding Homo_sapiens 0 597
ENST00000461408 ADAM10-003 protein_coding Homo_sapiens 6e-23 113
ENST00000462061 ADAM10-005 retained_intron Homo_sapiens 0 457
ENST00000470269 ADAM10-007 retained_intron Homo_sapiens 0 689
ENST00000475898 ADAM10-011 processed_transcript Homo_sapiens 0 614
ENST00000481164 ADAM10-004 retained_intron Homo_sapiens 0 278
ENST00000482945 ADAM10-008 retained_intron Homo_sapiens 0 1125
ENST00000497846 ADAM10-009 processed_transcript Homo_sapiens 0 747
ENST00000558004 ADAM10-013 protein_coding Homo_sapiens 0 403
ENST00000558733 ADAM10-015 processed_transcript Homo_sapiens 0 959
ENST00000559053 ADAM10-016 protein_coding Homo_sapiens 0 525
ENST00000560608 ADAM10-014 processed_transcript Homo_sapiens 0 401
ENST00000561149 ADAM10-012 processed_transcript Homo_sapiens 0 355
ENST00000561288 ADAM10-017 protein_coding Homo_sapiens 0 488

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