C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: E1A binding protein p300
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000068387 Ep300-001 ENSMUSG00000055024 10090 + 15:81586220-81652072 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068387
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068387 3.065±1.57 3.714±1.65 5.451±4.46 7.218±2.18 3.827±1.83 8.578±5.29 3.775±1.43 4.153±2.30 2.843±1.98 7.388±1.70 5.188±0.68 7.396±4.51 8.290±4.49 5.258±0.84

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006RK CIL_0006RK_0002 CGP 15:81585351-81688315

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000123 IDA histone acetyltransferase complex
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001047 IEA core promoter binding
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001666 ISS response to hypoxia
GO:0001756 IGI somitogenesis
GO:0002039 IPI p53 binding
GO:0003677 IDA DNA binding
GO:0003682 IEA chromatin binding
GO:0003713 ISS transcription coactivator activity
GO:0004402 ISS histone acetyltransferase activity
GO:0004468 ISS lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006475 ISS internal protein amino acid acetylation
GO:0006915 ISS apoptotic process
GO:0007049 IEA cell cycle
GO:0007507 IMP heart development
GO:0007519 IMP skeletal muscle tissue development
GO:0007623 IDA circadian rhythm
GO:0008013 IEA beta-catenin binding
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0009887 IMP organ morphogenesis
GO:0016407 ISS acetyltransferase activity
GO:0016746 IEA transferase activity, transferring acyl groups
GO:0018076 ISS N-terminal peptidyl-lysine acetylation
GO:0018393 IEA internal peptidyl-lysine acetylation
GO:0030154 IEA cell differentiation
GO:0030324 IMP lung development
GO:0031490 IDA chromatin DNA binding
GO:0032092 IDA positive regulation of protein binding
GO:0033613 IEA activating transcription factor binding
GO:0035257 IEA nuclear hormone receptor binding
GO:0042771 IEA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043627 ISS response to estrogen
GO:0043923 IEA positive regulation by host of viral transcription
GO:0043967 ISS histone H4 acetylation
GO:0043969 ISS histone H2B acetylation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0050681 IEA androgen receptor binding
GO:0051091 ISS positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051216 NAS cartilage development
GO:0060765 IEA regulation of androgen receptor signaling pathway
GO:0090043 ISS regulation of tubulin deacetylation
GO:0097157 IDA pre-mRNA intronic binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000087250 crebbpa-201 protein_coding Danio_rerio 0 1199
ENSDART00000148002 crebbpa-001 protein_coding Danio_rerio 0 1199
ENSDART00000091873 crebbpb-201 protein_coding Danio_rerio 0 1155
ENSDART00000115164 CREBBP (1 of 3)-201 protein_coding Danio_rerio 0 494
ENST00000262367 CREBBP-001 protein_coding Homo_sapiens 0 1533
ENST00000263253 EP300-001 protein_coding Homo_sapiens 0 10670
ENST00000382070 CREBBP-003 protein_coding Homo_sapiens 0 1533
ENST00000573517 CREBBP-011 protein_coding Homo_sapiens 0 239

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