C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fat mass and obesity associated
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000069718 Fto-001 ENSMUSG00000055932 10090 + 8:91313532-91668439 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069718
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069718 24.486±2.38 16.514±2.48 27.982±0.38 41.561±19.29 21.056±4.40 12.488±0.62 18.887±1.37 21.556±0.61 9.817±0.83 19.840±1.36 26.728±1.18 26.244±5.39 12.559±5.42 19.767±8.24

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ON CIL_0007ON_0003 UCNEbase 8:88447800-92743752
CIL_0007PV CIL_0007PV_0002 VISTA 8:90870647-91472060
CIL_0008IZ CIL_0008IZ_0002 VISTA 8:90885299-91486231
CIL_0007S1 CIL_0007S1_0002 VISTA 8:91005057-91606285
CIL_0007S0 CIL_0007S0_0002 VISTA 8:91042027-91642872
CIL_0007SA CIL_0007SA_0002 VISTA 8:91191445-91792009
CIL_0007X2 CIL_0007X2_0002 VISTA 8:91208767-91810326
CIL_0005OE CIL_0005OE_0002 CGP 8:91217030-91668439
CIL_0007X0 CIL_0007X0_0002 VISTA 8:91238298-91839821
CIL_0007WZ CIL_0007WZ_0002 VISTA 8:91245726-91847572
CIL_0000UO CIL_0000UO_0002 CGP 8:91313532-91801916

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001659 IMP temperature homeostasis
GO:0005634 IDA nucleus
GO:0006307 ISS DNA dealkylation involved in DNA repair
GO:0008198 ISS ferrous iron binding
GO:0010883 IMP regulation of lipid storage
GO:0016607 ISS nuclear speck
GO:0035515 IDA oxidative RNA demethylase activity
GO:0035516 IDA oxidative DNA demethylase activity
GO:0035552 IDA oxidative single-stranded DNA demethylation
GO:0035553 IDA oxidative single-stranded RNA demethylation
GO:0040014 IMP regulation of multicellular organism growth
GO:0042245 IDA RNA repair
GO:0043734 IDA DNA-N1-methyladenine dioxygenase activity
GO:0044065 IMP regulation of respiratory system process
GO:0060612 IMP adipose tissue development
GO:0070350 IMP regulation of white fat cell proliferation
GO:0070989 IDA oxidative demethylation
GO:0080111 IDA DNA demethylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000130028 fto-201 protein_coding Danio_rerio 0.0000000002 73
ENSDART00000064913 fto-001 protein_coding Danio_rerio 0.0000000002 73

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