C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin 6 signal transducer
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000070731 Il6st-201 ENSMUSG00000021756 10090 + 13:112475008-112506860 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070731
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070731 30.557±9.67 27.566±3.93 53.032±11.82 2.584±0.58 23.225±2.32 11.985±1.50 17.460±0.51 8.460±1.29 4.174±2.23 30.976±2.38 22.233±1.26 22.440±2.48 14.029±6.76 1.495±0.35

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004921 IDA interleukin-11 receptor activity
GO:0005515 IPI protein binding
GO:0005977 IMP glycogen metabolic process
GO:0007165 IDA signal transduction
GO:0008284 IGI positive regulation of cell proliferation
GO:0008593 IDA regulation of Notch signaling pathway
GO:0009897 IDA external side of plasma membrane
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019970 IDA interleukin-11 binding
GO:0030425 IDA dendrite
GO:0038154 IDA interleukin-11-mediated signaling pathway
GO:0043025 IDA neuronal cell body
GO:0044297 IDA cell body
GO:0048711 IMP positive regulation of astrocyte differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000336909 IL6ST-201 protein_coding Homo_sapiens 0 1967
ENST00000346911 IL6STP1-001 processed_pseudogene Homo_sapiens 0 329
ENST00000381286 IL6ST-005 protein_coding Homo_sapiens 0 204
ENST00000381287 IL6ST-202 protein_coding Homo_sapiens 0 1399
ENST00000381293 IL6ST-003 protein_coding Homo_sapiens 0 206
ENST00000381294 IL6ST-012 protein_coding Homo_sapiens 0 1116
ENST00000381298 IL6ST-001 protein_coding Homo_sapiens 0 1962
ENST00000502326 IL6ST-011 protein_coding Homo_sapiens 0 1881
ENST00000503773 IL6ST-006 nonsense_mediated_decay Homo_sapiens 0 1367
ENST00000522633 IL6ST-007 protein_coding Homo_sapiens 0 516
ENST00000523039 IL6ST-010 retained_intron Homo_sapiens 0 499
ENST00000583149 IL6ST-013 retained_intron Homo_sapiens 0 538

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