C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: gap junction protein, alpha 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000072600 Gja5-001 ENSMUSG00000057123 10090 + 3:97032416-97053634 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072600
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072600 11.107±4.66 1.365±0.24 1.871±0.18 0.545±0.37 2.922±0.66 1.433±0.37 8.846±1.17 3.422±0.93 1.066±0.73 21.323±1.34 1.086±0.13 2.019±0.53 2.900±2.04 0.350±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004D1 CIL_0004D1_0002 CGP 3:96918863-97053634
CIL_0006WY CIL_0006WY_0002 CGP 3:97032416-97176574

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0003071 IMP renal system process involved in regulation of systemic arterial blood pressure
GO:0003073 IMP regulation of systemic arterial blood pressure
GO:0003105 IEA negative regulation of glomerular filtration
GO:0003151 IEA outflow tract morphogenesis
GO:0003158 IEA endothelium development
GO:0003161 IMP cardiac conduction system development
GO:0003174 IEA mitral valve development
GO:0003193 IEA pulmonary valve formation
GO:0003281 IEA ventricular septum development
GO:0003283 IEA atrial septum development
GO:0003284 IMP septum primum development
GO:0003294 IMP atrial ventricular junction remodeling
GO:0005243 IEA gap junction channel activity
GO:0005887 IEA integral component of plasma membrane
GO:0005921 IDA gap junction
GO:0005922 IEA connexon complex
GO:0006813 IEA potassium ion transport
GO:0007507 IEA heart development
GO:0010643 IEA cell communication by chemical coupling
GO:0010644 IEA cell communication by electrical coupling
GO:0010652 IEA positive regulation of cell communication by chemical coupling
GO:0014704 IEA intercalated disc
GO:0016264 IEA gap junction assembly
GO:0030326 IMP embryonic limb morphogenesis
GO:0035050 IMP embryonic heart tube development
GO:0035922 IMP foramen ovale closure
GO:0042312 IMP regulation of vasodilation
GO:0042995 IEA cell projection
GO:0045776 IEA negative regulation of blood pressure
GO:0045907 IEA positive regulation of vasoconstriction
GO:0045909 IEA positive regulation of vasodilation
GO:0048844 IMP artery morphogenesis
GO:0051259 IEA protein oligomerization
GO:0055077 IEA gap junction hemi-channel activity
GO:0055085 IEA transmembrane transport
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0060307 IGI regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371 IMP regulation of atrial cardiac muscle cell membrane depolarization
GO:0060373 IMP regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060412 IMP ventricular septum morphogenesis
GO:0060413 IMP atrial septum morphogenesis
GO:0061337 IMP cardiac conduction
GO:0071253 IEA connexin binding
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086014 IEA atrial cardiac muscle cell action potential
GO:0086015 IMP SA node cell action potential
GO:0086053 IEA AV node cell to bundle of His cell communication by electrical coupling
GO:0086064 IMP cell communication by electrical coupling involved in cardiac conduction
GO:0086065 IMP cell communication involved in cardiac conduction
GO:0086067 IMP AV node cell to bundle of His cell communication
GO:0086069 IEA bundle of His cell to Purkinje myocyte communication
GO:0086075 IEA gap junction channel activity involved in cardiac conduction electrical coupling
GO:0086077 IEA gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1900133 IMP regulation of renin secretion into blood stream
GO:1900825 IMP regulation of membrane depolarization during cardiac muscle cell action potential
GO:1990029 IEA vasomotion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000430508 GJA5-002 protein_coding Homo_sapiens 0 798
ENST00000579774 GJA5-001 protein_coding Homo_sapiens 0 970
ENST00000621517 GJA5-201 protein_coding Homo_sapiens 0 996

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