C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: gap junction protein, alpha 5, 40kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000621517 GJA5-201 ENSG00000265107 9606 - 1:147756200-147773362 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000621517
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000621517 11.768±0.00 3.951±0.00 0.817±0.00 3.194±2.44 5.010±0.00 4.807±0.00 7.016±0.00 0.681±0.21 4.291±1.32 0.531±0.00 2.351±1.41 13.120±0.00 2.980±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000UA CIL_0000UA_0002 CGP 1:147756199-147909257

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0001525 IEP angiogenesis
GO:0001568 IEA blood vessel development
GO:0003071 IEA renal system process involved in regulation of systemic arterial blood pressure
GO:0003073 IEA regulation of systemic arterial blood pressure
GO:0003105 IEA negative regulation of glomerular filtration
GO:0003151 IMP outflow tract morphogenesis
GO:0003158 IEA endothelium development
GO:0003161 IEA cardiac conduction system development
GO:0003174 IMP mitral valve development
GO:0003193 IMP pulmonary valve formation
GO:0003281 IMP ventricular septum development
GO:0003283 IMP atrial septum development
GO:0003284 IEA septum primum development
GO:0003294 IEA atrial ventricular junction remodeling
GO:0005243 IEA gap junction channel activity
GO:0005887 IDA integral component of plasma membrane
GO:0005921 IDA gap junction
GO:0005922 IDA connexon complex
GO:0006813 IEA potassium ion transport
GO:0007507 IEA heart development
GO:0010643 IEA cell communication by chemical coupling
GO:0010644 IEA cell communication by electrical coupling
GO:0010652 IEA positive regulation of cell communication by chemical coupling
GO:0014704 IDA intercalated disc
GO:0016264 IMP gap junction assembly
GO:0030326 IEA embryonic limb morphogenesis
GO:0035050 IEA embryonic heart tube development
GO:0035922 IEA foramen ovale closure
GO:0042312 IEA regulation of vasodilation
GO:0042995 IEA cell projection
GO:0045776 IEA negative regulation of blood pressure
GO:0045907 IEA positive regulation of vasoconstriction
GO:0045909 IEA positive regulation of vasodilation
GO:0048844 ISS artery morphogenesis
GO:0051259 IEA protein oligomerization
GO:0055077 IDA gap junction hemi-channel activity
GO:0055085 IDA transmembrane transport
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060307 IEA regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371 IMP regulation of atrial cardiac muscle cell membrane depolarization
GO:0060373 IEA regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060412 IEA ventricular septum morphogenesis
GO:0060413 IEA atrial septum morphogenesis
GO:0061337 IEA cardiac conduction
GO:0071253 IEA connexin binding
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0086014 IMP atrial cardiac muscle cell action potential
GO:0086015 IEA SA node cell action potential
GO:0086053 IMP AV node cell to bundle of His cell communication by electrical coupling
GO:0086064 IDA cell communication by electrical coupling involved in cardiac conduction
GO:0086065 IEA cell communication involved in cardiac conduction
GO:0086067 IEA AV node cell to bundle of His cell communication
GO:0086069 IMP bundle of His cell to Purkinje myocyte communication
GO:0086075 IMP gap junction channel activity involved in cardiac conduction electrical coupling
GO:0086077 IDA gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:1900133 IEA regulation of renin secretion into blood stream
GO:1900825 IEA regulation of membrane depolarization during cardiac muscle cell action potential
GO:1990029 IEA vasomotion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000072600 Gja5-001 protein_coding Mus_musculus 0 996
ENSMUST00000062944 Gja8-201 protein_coding Mus_musculus 0 195

Loading