C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inositol polyphosphate-5-phosphatase D
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000072999 Inpp5d-004 ENSMUSG00000026288 10090 + 1:87620398-87720503 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartLiverMuscleENSMUST00000072999
Transcript ID Heart Liver Muscle
ENSMUST00000072999 0.979±0.00 0.168±0.00 0.222±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003HY CIL_0003HY_0002 CGP 1:87509889-87720507
CIL_0003HZ CIL_0003HZ_0002 CGP 1:87620312-87792428

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004445 IDA inositol-polyphosphate 5-phosphatase activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006915 IEA apoptotic process
GO:0008285 IDA negative regulation of cell proliferation
GO:0008340 IMP determination of adult lifespan
GO:0009968 IMP negative regulation of signal transduction
GO:0016064 IMP immunoglobulin mediated immune response
GO:0017124 IDA SH3 domain binding
GO:0030853 IMP negative regulation of granulocyte differentiation
GO:0030889 IMP negative regulation of B cell proliferation
GO:0034594 IDA phosphatidylinositol trisphosphate phosphatase activity
GO:0035556 IMP intracellular signal transduction
GO:0043065 IMP positive regulation of apoptotic process
GO:0045409 IMP negative regulation of interleukin-6 biosynthetic process
GO:0045579 IMP positive regulation of B cell differentiation
GO:0045621 IMP positive regulation of lymphocyte differentiation
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0045656 IMP negative regulation of monocyte differentiation
GO:0045659 IMP negative regulation of neutrophil differentiation
GO:0045671 IMP negative regulation of osteoclast differentiation
GO:0045779 IMP negative regulation of bone resorption
GO:0046856 IEA phosphatidylinositol dephosphorylation
GO:0050777 IMP negative regulation of immune response
GO:0050869 IMP negative regulation of B cell activation
GO:0051425 IDA PTB domain binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000359570 INPP5D-001 protein_coding Homo_sapiens 0 3171
ENST00000415617 INPP5D-015 protein_coding Homo_sapiens 0 1882
ENST00000445964 INPP5D-006 protein_coding Homo_sapiens 0 3162
ENST00000451407 INPP5D-016 retained_intron Homo_sapiens 0 813
ENST00000465281 INPP5D-010 retained_intron Homo_sapiens 0 516
ENST00000467393 INPP5D-003 processed_transcript Homo_sapiens 0 311
ENST00000474278 INPP5D-004 processed_transcript Homo_sapiens 0 424
ENST00000493078 INPP5D-012 retained_intron Homo_sapiens 0 390
ENST00000493632 INPP5D-008 retained_intron Homo_sapiens 0 597

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