C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inositol polyphosphate-5-phosphatase, 145kDa
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000445964 INPP5D-006 ENSG00000168918 9606 + 2:233060398-233207902 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000445964
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000445964 3.895±0.00 20.642±0.00 1.488±0.17 1.854±0.16 1.533±0.47 0.433±0.23 0.961±0.00 0.874±0.51 4.223±0.28 0.540±0.00 2.925±2.35 5.171±1.12 0.837±0.37

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003HY CIL_0003HY_0001 CGP 2:233032672-233207903
CIL_0003HZ CIL_0003HZ_0001 CGP 2:233059967-233295674

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004445 IEA inositol-polyphosphate 5-phosphatase activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0006796 TAS phosphate-containing compound metabolic process
GO:0006915 IEA apoptotic process
GO:0007165 TAS signal transduction
GO:0007596 TAS blood coagulation
GO:0008285 IEA negative regulation of cell proliferation
GO:0008340 IEA determination of adult lifespan
GO:0009968 IEA negative regulation of signal transduction
GO:0016020 IEA membrane
GO:0016064 IEA immunoglobulin mediated immune response
GO:0016311 IEA dephosphorylation
GO:0017124 IEA SH3 domain binding
GO:0030853 IEA negative regulation of granulocyte differentiation
GO:0030889 IEA negative regulation of B cell proliferation
GO:0034594 IEA phosphatidylinositol trisphosphate phosphatase activity
GO:0035556 IEA intracellular signal transduction
GO:0043065 IEA positive regulation of apoptotic process
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045409 IEA negative regulation of interleukin-6 biosynthetic process
GO:0045579 IEA positive regulation of B cell differentiation
GO:0045621 IEA positive regulation of lymphocyte differentiation
GO:0045648 IEA positive regulation of erythrocyte differentiation
GO:0045656 IEA negative regulation of monocyte differentiation
GO:0045659 IEA negative regulation of neutrophil differentiation
GO:0045671 IEA negative regulation of osteoclast differentiation
GO:0045779 IEA negative regulation of bone resorption
GO:0046856 IEA phosphatidylinositol dephosphorylation
GO:0050777 IEA negative regulation of immune response
GO:0050852 TAS T cell receptor signaling pathway
GO:0050869 IEA negative regulation of B cell activation
GO:0050900 TAS leukocyte migration
GO:0051425 IEA PTB domain binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000169754 Inpp5d-001 protein_coding Mus_musculus 0 3585
ENSMUST00000042275 Inpp5d-002 protein_coding Mus_musculus 0 3572
ENSMUST00000168783 Inpp5d-003 protein_coding Mus_musculus 0 3177
ENSMUST00000072999 Inpp5d-004 nonsense_mediated_decay Mus_musculus 0 3162
ENSMUST00000167032 Inpp5d-005 protein_coding Mus_musculus 0 2872
ENSMUST00000170300 Inpp5d-006 protein_coding Mus_musculus 0 2464
ENSMUST00000163548 Inpp5d-011 processed_transcript Mus_musculus 0 350
ENSMUST00000165554 Inpp5d-009 protein_coding Mus_musculus 0 339
ENSMUST00000163576 Inpp5d-010 protein_coding Mus_musculus 0 298
ENSMUST00000163222 Inpp5d-008 retained_intron Mus_musculus 0 294
ENSMUST00000164592 Inpp5d-007 processed_transcript Mus_musculus 0 292

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