C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neuroligin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000075054 Nlgn1-201 ENSMUSG00000063887 10090 - 3:25431811-26133734 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLiverLungMuscleENSMUST00000075054
Transcript ID Brain Liver Lung Muscle
ENSMUST00000075054 1.972±0.92 0.002±0.00 0.022±0.00 0.020±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002087 IGI regulation of respiratory gaseous exchange by neurological system process
GO:0004872 IBA receptor activity
GO:0005515 IPI protein binding
GO:0005887 IMP integral component of plasma membrane
GO:0007157 IDA heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007158 IDA neuron cell-cell adhesion
GO:0007399 IDA nervous system development
GO:0007416 IDA synapse assembly
GO:0009897 IDA external side of plasma membrane
GO:0009986 ISS cell surface
GO:0016080 IMP synaptic vesicle targeting
GO:0016339 ISS calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0030054 IEA cell junction
GO:0030425 ISS dendrite
GO:0032230 ISS positive regulation of synaptic transmission, GABAergic
GO:0032433 ISS filopodium tip
GO:0035418 IDA protein localization to synapse
GO:0042043 IMP neurexin family protein binding
GO:0045184 IMP establishment of protein localization
GO:0045202 ISS synapse
GO:0045211 IEA postsynaptic membrane
GO:0045664 IDA regulation of neuron differentiation
GO:0046983 ISS protein dimerization activity
GO:0048789 IMP cytoskeletal matrix organization at active zone
GO:0050804 IGI regulation of synaptic transmission
GO:0050808 ISO synapse organization
GO:0051260 IDA protein homooligomerization
GO:0051491 ISS positive regulation of filopodium assembly
GO:0051965 ISS positive regulation of synapse assembly
GO:0051968 ISS positive regulation of synaptic transmission, glutamatergic
GO:0060076 IC excitatory synapse
GO:0060999 ISS positive regulation of dendritic spine development
GO:0072553 IMP terminal button organization
GO:0097091 IDA synaptic vesicle clustering
GO:0097104 IDA postsynaptic membrane assembly
GO:0097105 IDA presynaptic membrane assembly
GO:0097113 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering
GO:0097114 ISS N-methyl-D-aspartate receptor clustering
GO:0097115 IDA neurexin clustering
GO:0097119 IDA postsynaptic density protein 95 clustering
GO:0097120 IDA receptor localization to synapse
GO:1900244 IMP positive regulation of synaptic vesicle endocytosis
GO:2000302 IMP positive regulation of synaptic vesicle exocytosis
GO:2000310 IDA regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 IDA positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000113171 nlgn1-201 protein_coding Danio_rerio 0 970
ENST00000361589 NLGN1-002 protein_coding Homo_sapiens 0 3812
ENST00000401917 NLGN1-201 protein_coding Homo_sapiens 0 2560
ENST00000415045 NLGN1-003 protein_coding Homo_sapiens 0 787
ENST00000457714 NLGN1-001 protein_coding Homo_sapiens 0 3812
ENST00000466350 NLGN1-010 processed_transcript Homo_sapiens 0 1013
ENST00000469564 NLGN1-011 processed_transcript Homo_sapiens 0 363
ENST00000469727 NLGN1-006 processed_transcript Homo_sapiens 0 300
ENST00000490929 NLGN1-008 processed_transcript Homo_sapiens 0 248

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