C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neuroligin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000457714 NLGN1-001 ENSG00000169760 9606 + 3:173398448-174286644 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastOvaryPlacentaTestisENST00000457714
Transcript ID Breast Ovary Placenta Testis
ENST00000457714 0.050±0.00 0.130±0.00 0.046±0.00 0.136±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002087 IEA regulation of respiratory gaseous exchange by neurological system process
GO:0004872 ISS receptor activity
GO:0005515 IEA protein binding
GO:0005887 ISS integral component of plasma membrane
GO:0006605 ISS protein targeting
GO:0007157 ISS heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007158 ISS neuron cell-cell adhesion
GO:0007399 ISS nervous system development
GO:0007416 ISS synapse assembly
GO:0008152 IEA metabolic process
GO:0009897 IEA external side of plasma membrane
GO:0009986 ISS cell surface
GO:0016080 ISS synaptic vesicle targeting
GO:0016339 ISS calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016787 IEA hydrolase activity
GO:0017146 IEA N-methyl-D-aspartate selective glutamate receptor complex
GO:0023041 TAS neuronal signal transduction
GO:0030054 IEA cell junction
GO:0030165 IDA PDZ domain binding
GO:0030425 ISS dendrite
GO:0032230 ISS positive regulation of synaptic transmission, GABAergic
GO:0032433 ISS filopodium tip
GO:0035418 ISS protein localization to synapse
GO:0042043 ISS neurexin family protein binding
GO:0045184 ISS establishment of protein localization
GO:0045202 ISS synapse
GO:0045211 IEA postsynaptic membrane
GO:0045664 ISS regulation of neuron differentiation
GO:0046983 ISS protein dimerization activity
GO:0048789 ISS cytoskeletal matrix organization at active zone
GO:0050804 IEA regulation of synaptic transmission
GO:0050808 IEA synapse organization
GO:0050839 ISS cell adhesion molecule binding
GO:0051260 ISS protein homooligomerization
GO:0051290 IEA protein heterotetramerization
GO:0051491 ISS positive regulation of filopodium assembly
GO:0051965 ISS positive regulation of synapse assembly
GO:0051968 ISS positive regulation of synaptic transmission, glutamatergic
GO:0060999 ISS positive regulation of dendritic spine development
GO:0072553 ISS terminal button organization
GO:0097091 ISS synaptic vesicle clustering
GO:0097104 ISS postsynaptic membrane assembly
GO:0097105 ISS presynaptic membrane assembly
GO:0097113 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering
GO:0097114 ISS N-methyl-D-aspartate receptor clustering
GO:0097115 ISS neurexin clustering
GO:0097119 ISS postsynaptic density protein 95 clustering
GO:0097120 ISS receptor localization to synapse
GO:0097481 TAS neuronal postsynaptic density
GO:1900029 ISS positive regulation of ruffle assembly
GO:1900244 ISS positive regulation of synaptic vesicle endocytosis
GO:1902533 ISS positive regulation of intracellular signal transduction
GO:2000302 ISS positive regulation of synaptic vesicle exocytosis
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000075054 Nlgn1-201 protein_coding Mus_musculus 0 3812
ENSMUST00000108308 Nlgn1-202 protein_coding Mus_musculus 0 3323
ENSDART00000113171 nlgn1-201 protein_coding Danio_rerio 0 922

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