C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000415288 ERBB3-024 ENSG00000065361 9606 + 12:56083319-56102336 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonKidneyLungOvaryENST00000415288
Transcript ID Bladder Breast Colon Kidney Lung Ovary
ENST00000415288 4.799±0.00 4.043±0.00 6.569±0.00 8.013±0.00 4.070±0.00 12.312±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002TJ CIL_0002TJ_0003 CGP 12:56079857-56109289

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0004716 IEA receptor signaling protein tyrosine kinase activity
GO:0004888 ISS transmembrane signaling receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007162 IDA negative regulation of cell adhesion
GO:0007165 IDA signal transduction
GO:0007169 ISS:IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007422 ISS peripheral nervous system development
GO:0007507 ISS heart development
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009968 IDA negative regulation of signal transduction
GO:0014037 ISS Schwann cell differentiation
GO:0014065 IDA phosphatidylinositol 3-kinase signaling
GO:0014068 TAS positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019838 IPI growth factor binding
GO:0021545 ISS cranial nerve development
GO:0030296 IDA protein tyrosine kinase activator activity
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042060 NAS wound healing
GO:0042127 IDA regulation of cell proliferation
GO:0042802 IPI identical protein binding
GO:0042803 NAS protein homodimerization activity
GO:0043235 IDA receptor complex
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0045087 TAS innate immune response
GO:0046982 IDA protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0051048 IDA negative regulation of secretion
GO:0051402 IMP neuron apoptotic process
GO:0061098 IMP positive regulation of protein tyrosine kinase activity
GO:0097192 IMP extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000082059 Erbb3-001 protein_coding Mus_musculus 0 4458

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