C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dedicator of cytokinesis 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000084488 Dock1-201 ENSMUSG00000058325 10090 + 7:134670687-135173639 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000084488
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000084488 9.974±1.93 22.454±3.10 7.232±0.40 3.942±0.93 5.655±0.96 7.241±0.83 4.161±0.39 10.522±0.39 1.682±0.46 10.792±1.68 0.811±0.13 10.589±2.45 7.585±2.73 0.957±0.40

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047A CIL_00047A_0003 CGP 7:134266262-135173639
CIL_00047B CIL_00047B_0003 CGP 7:134670687-135173639

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002244 IGI hematopoietic progenitor cell differentiation
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006909 IEA phagocytosis
GO:0006915 IEA apoptotic process
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 IEA membrane
GO:0016477 IDA cell migration
GO:0017124 IEA SH3 domain binding
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000109740 dock1-201 protein_coding Danio_rerio 0 1236
ENST00000256935 DOCK2-001 protein_coding Homo_sapiens 2e-32 147
ENST00000280333 DOCK1-001 protein_coding Homo_sapiens 0 6499
ENST00000473861 DOCK1-002 retained_intron Homo_sapiens 0 353
ENST00000484400 DOCK1-003 processed_transcript Homo_sapiens 0 510
ENST00000520908 DOCK2-004 protein_coding Homo_sapiens 8e-30 137
ENST00000524185 DOCK2-002 nonsense_mediated_decay Homo_sapiens 2e-32 147
ENST00000623213 DOCK1-006 protein_coding Homo_sapiens 0 5171

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