C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000591517 MAP4K1-002 ENSG00000104814 9606 - 19:38587641-38617924 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastKidneyLiverOvaryPlacentaTestisENST00000591517
Transcript ID Adipose Adrenal Brain Breast Kidney Liver Ovary Placenta Testis
ENST00000591517 0.572±0.00 5.823±0.00 0.427±0.00 1.612±0.00 0.712±0.00 0.284±0.00 0.271±0.06 1.052±0.59 0.379±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000185 IC activation of MAPKKK activity
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0006468 IDA:IEA protein phosphorylation
GO:0006950 IDA response to stress
GO:0007257 TAS activation of JUN kinase activity
GO:0008283 IMP cell proliferation
GO:0008349 IDA MAP kinase kinase kinase kinase activity
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0035556 IDA intracellular signal transduction
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000085835 Map4k1-201 protein_coding Mus_musculus 0 2335
ENSDART00000029824 map4k5-001 protein_coding Danio_rerio 3e-27 128

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