C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: AXL receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000085948 Axl-002 ENSMUSG00000002602 10090 - 7:25757630-25788705 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLungOvaryPlacentaTestisENSMUST00000085948
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Lung Ovary Placenta Testis
ENSMUST00000085948 9.714±4.35 5.190±0.79 7.305±0.00 16.296±1.95 8.076±1.10 2.200±0.51 6.476±1.34 18.210±6.24 5.446±3.75 2.844±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TR CIL_0008TR_0002 VISTA 7:25324415-25925712
CIL_0006UR CIL_0006UR_0002 CGP 7:25757273-25816913

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IGI neuron migration
GO:0001779 IGI natural killer cell differentiation
GO:0001974 IMP blood vessel remodeling
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0006909 IGI phagocytosis
GO:0006954 IMP inflammatory response
GO:0007167 IGI enzyme linked receptor protein signaling pathway
GO:0007283 IGI spermatogenesis
GO:0016021 IEA integral component of membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021885 IGI forebrain cell migration
GO:0030168 IMP platelet activation
GO:0031668 IDA cellular response to extracellular stimulus
GO:0032720 IGI negative regulation of tumor necrosis factor production
GO:0032940 IMP secretion by cell
GO:0034101 IGI erythrocyte homeostasis
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0042698 IGI ovulation cycle
GO:0043066 IMP negative regulation of apoptotic process
GO:0043277 IGI apoptotic cell clearance
GO:0043491 IGI protein kinase B signaling
GO:0043524 IGI negative regulation of neuron apoptotic process
GO:0046982 IPI protein heterodimerization activity
GO:0051250 IGI negative regulation of lymphocyte activation
GO:0060068 IGI vagina development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000301178 AXL-001 protein_coding Homo_sapiens 0 2826
ENST00000359092 AXL-002 protein_coding Homo_sapiens 0 2955
ENST00000593513 AXL-004 protein_coding Homo_sapiens 0 2294
ENST00000599659 AXL-003 retained_intron Homo_sapiens 0 1232

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