C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nitric oxide synthase 1 (neuronal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000618760 NOS1-202 ENSG00000089250 9606 - 12:117208144-117361802 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastMuscleOvaryPlacentaENST00000618760
Transcript ID Breast Muscle Ovary Placenta
ENST00000618760 0.398±0.00 1.623±0.00 0.003±0.00 0.001±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001QM CIL_0001QM_0002 CGP 12:117208142-117968983

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEP response to hypoxia
GO:0001917 ISS photoreceptor inner segment
GO:0002028 ISS regulation of sodium ion transport
GO:0003958 IBA NADPH-hemoprotein reductase activity
GO:0004517 ISS:IEA nitric-oxide synthase activity
GO:0005506 IEA iron ion binding
GO:0005515 IPI:IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005737 TAS cytoplasm
GO:0005739 ISS mitochondrion
GO:0005829 TAS cytosol
GO:0005856 ISS cytoskeleton
GO:0006527 IC arginine catabolic process
GO:0006809 IBA:IEA nitric oxide biosynthetic process
GO:0006941 ISS striated muscle contraction
GO:0007263 IBA nitric oxide mediated signal transduction
GO:0007520 TAS myoblast fusion
GO:0007596 TAS blood coagulation
GO:0009408 IDA response to heat
GO:0010181 ISS:IEA FMN binding
GO:0010523 TAS negative regulation of calcium ion transport into cytosol
GO:0016491 IBA:IEA oxidoreductase activity
GO:0016529 IDA sarcoplasmic reticulum
GO:0017080 ISS sodium channel regulator activity
GO:0018119 ISS peptidyl-cysteine S-nitrosylation
GO:0020037 ISS:IEA heme binding
GO:0031284 IBA positive regulation of guanylate cyclase activity
GO:0033555 IMP multicellular organismal response to stress
GO:0034617 NAS tetrahydrobiopterin binding
GO:0034618 TAS arginine binding
GO:0035066 ISS positive regulation of histone acetylation
GO:0042136 TAS neurotransmitter biosynthetic process
GO:0042383 IDA sarcolemma
GO:0042738 ISS exogenous drug catabolic process
GO:0042995 IEA cell projection
GO:0043234 ISS protein complex
GO:0043267 ISS negative regulation of potassium ion transport
GO:0044325 ISS ion channel binding
GO:0045121 ISS membrane raft
GO:0045202 ISS synapse
GO:0045776 IBA negative regulation of blood pressure
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045909 IDA positive regulation of vasodilation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046870 ISS cadmium ion binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0050660 ISS:IEA flavin adenine dinucleotide binding
GO:0050661 ISS:IEA NADP binding
GO:0051346 ISS negative regulation of hydrolase activity
GO:0051612 ISS negative regulation of serotonin uptake
GO:0051701 TAS interaction with host
GO:0051926 ISS negative regulation of calcium ion transport
GO:0055114 IEA oxidation-reduction process
GO:0055117 TAS regulation of cardiac muscle contraction
GO:0071363 ISS cellular response to growth factor stimulus
GO:0090382 TAS phagosome maturation
GO:0097110 ISS scaffold protein binding
GO:0098735 ISS positive regulation of the force of heart contraction
GO:1901206 IEA positive regulation of adrenergic receptor signaling pathway involved in heart process
GO:1902307 ISS positive regulation of sodium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102557 Nos1-002 protein_coding Mus_musculus 0 4970
ENSMUST00000171055 Nos1-201 protein_coding Mus_musculus 0 2641
ENSMUST00000086451 Nos1-003 nonsense_mediated_decay Mus_musculus 0 2641
ENSMUST00000142742 Nos1-001 protein_coding Mus_musculus 0 2641
ENSDART00000099822 nos1-001 protein_coding Danio_rerio 0 669
ENSDART00000099810 nos1-201 protein_coding Danio_rerio 0 664
ENSMUST00000138554 Nos1-006 processed_transcript Mus_musculus 0 531
ENSMUST00000018610 Nos2-001 protein_coding Mus_musculus 0 453
ENSMUST00000037912 Ssh2-001 protein_coding Mus_musculus 0.00000003 68
ENSMUST00000074912 2010012O05Rik-201 protein_coding Mus_musculus 0.000001 62

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