C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: anaplastic lymphoma kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000086639 Alk-201 ENSMUSG00000055471 10090 - 17:71869442-72603709 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086639
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086639 0.005±0.00 0.016±0.01 0.017±0.01 0.638±0.26 0.086±0.03 0.112±0.04 0.005±0.00 0.026±0.01 0.015±0.01 0.015±0.01 0.006±0.00 0.027±0.01 0.014±0.00 0.204±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00013T CIL_00013T_0002 CGP 17:71781947-72603709
CIL_0000VI CIL_0000VI_0002 CGP 17:71869442-72851195

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0004714 ISS transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005887 ISS integral component of plasma membrane
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 IEA nervous system development
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0043234 ISO protein complex
GO:0048666 IEA neuron development
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000061547 ltk-002 protein_coding Danio_rerio 0 494
ENSDART00000062907 ltk-001 protein_coding Danio_rerio 0 494
ENST00000389048 ALK-001 protein_coding Homo_sapiens 0 4806
ENST00000431873 ALK-201 protein_coding Homo_sapiens 0 1404
ENST00000453137 ALK-002 protein_coding Homo_sapiens 0 265
ENST00000618119 ALK-202 protein_coding Homo_sapiens 0 4276

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