C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: notch 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000087723 Notch3-001 ENSMUSG00000038146 10090 - 17:32120820-32166880 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000087723
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000087723 20.447±5.43 3.439±3.57 8.873±1.38 7.107±3.74 27.242±6.49 4.626±0.75 9.138±0.55 5.467±1.15 0.533±0.11 39.154±0.88 2.923±0.67 15.353±5.12 1.726±1.41 0.404±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043D CIL_00043D_0002 CGP 17:32120820-32189549

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007219 IC Notch signaling pathway
GO:0015629 IEA actin cytoskeleton
GO:0019899 IPI enzyme binding
GO:0030900 IGI forebrain development
GO:0043235 ISO receptor complex
GO:0045596 IMP negative regulation of cell differentiation
GO:0045665 IMP negative regulation of neuron differentiation
GO:0048661 IDA positive regulation of smooth muscle cell proliferation
GO:0048663 IGI neuron fate commitment
GO:0072104 IEP glomerular capillary formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263388 NOTCH3-001 protein_coding Homo_sapiens 0 7217
ENST00000595514 NOTCH3-005 nonsense_mediated_decay Homo_sapiens 0 438
ENST00000597756 NOTCH3-006 protein_coding Homo_sapiens 0 540
ENST00000600841 NOTCH3-004 retained_intron Homo_sapiens 0 337
ENST00000601011 NOTCH3-002 protein_coding Homo_sapiens 0 2573

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