C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: notch 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263388 NOTCH3-001 ENSG00000074181 9606 - 19:15159038-15200981 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000263388
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000263388 97.905±0.00 29.131±0.00 2.040±0.00 2.636±0.00 24.931±22.60 7.783±7.53 2.337±0.00 1.845±1.66 0.679±0.53 3.167±0.80 6.514±5.22 23.895±10.57 11.686±10.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00043D CIL_00043D_0001 CGP 19:15159038-15233435

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007219 TAS:IEA Notch signaling pathway
GO:0007220 TAS Notch receptor processing
GO:0007275 IEA multicellular organismal development
GO:0010467 TAS gene expression
GO:0015629 IDA actin cytoskeleton
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019899 IEA enzyme binding
GO:0030154 IEA cell differentiation
GO:0030900 IEA forebrain development
GO:0043235 IDA receptor complex
GO:0045596 IEA negative regulation of cell differentiation
GO:0045665 IEA negative regulation of neuron differentiation
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0048663 IEA neuron fate commitment
GO:0050793 IEA regulation of developmental process
GO:0072104 IEA glomerular capillary formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000087723 Notch3-001 protein_coding Mus_musculus 0 7217
ENSDART00000073930 notch3-001 protein_coding Danio_rerio 0 678
ENSMUST00000069431 Gm9978-201 protein_coding Mus_musculus 9e-22 111

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