C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mediator complex subunit 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000087948 Med12-001 ENSMUSG00000079487 10090 + X:101274260-101297465 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000087948
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000087948 6.534±2.36 5.457±0.23 5.832±0.51 9.316±3.06 7.054±1.89 4.747±0.81 3.200±0.63 3.171±0.63 3.703±2.75 9.421±1.60 2.735±0.71 10.434±3.63 8.307±3.30 3.799±0.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00057U CIL_00057U_0002 CGP X:101264378-101297465
CIL_00057X CIL_00057X_0002 CGP X:101274030-101325963

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001190 IGI RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001843 IMP neural tube closure
GO:0003682 IDA chromatin binding
GO:0003712 IEA transcription cofactor activity
GO:0003713 IEA transcription coactivator activity
GO:0004872 IEA receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006367 IEA transcription initiation from RNA polymerase II promoter
GO:0007507 IMP heart development
GO:0008013 IEA beta-catenin binding
GO:0008022 IEA protein C-terminus binding
GO:0008134 IPI transcription factor binding
GO:0014003 IMP oligodendrocyte development
GO:0014044 IMP Schwann cell development
GO:0016020 IEA membrane
GO:0016592 IDA mediator complex
GO:0019827 IMP stem cell maintenance
GO:0019904 IEA protein domain specific binding
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0030518 IEA intracellular steroid hormone receptor signaling pathway
GO:0030521 IEA androgen receptor signaling pathway
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046966 IEA thyroid hormone receptor binding
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060071 IMP Wnt signaling pathway, planar cell polarity pathway
GO:0090245 IMP axis elongation involved in somitogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000333646 MED12-201 protein_coding Homo_sapiens 0 9138
ENST00000374080 MED12-002 protein_coding Homo_sapiens 0 9075
ENST00000374102 MED12-001 protein_coding Homo_sapiens 0 9060
ENST00000429213 MED12-005 protein_coding Homo_sapiens 0 473
ENST00000444034 MED12-010 protein_coding Homo_sapiens 0 640
ENST00000460771 MED12-009 processed_transcript Homo_sapiens 0 468
ENST00000462984 MED12-007 processed_transcript Homo_sapiens 0 592
ENST00000471663 MED12-006 processed_transcript Homo_sapiens 0 516
ENST00000489199 MED12-008 processed_transcript Homo_sapiens 0 313

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