C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: membrane associated guanylate kinase, WW and PDZ domain containing 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354212 MAGI2-001 ENSG00000187391 9606 - 7:78017076-79453574 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonLiverENST00000354212
Transcript ID Bladder Breast Colon Liver
ENST00000354212 1.229±0.00 0.710±0.00 0.800±0.21 1.329±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008S6 CIL_0008S6_0001 VISTA 7:77922679-78523685

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002092 IDA positive regulation of receptor internalization
GO:0003402 NAS planar cell polarity pathway involved in axis elongation
GO:0004871 IEA signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005770 ISS late endosome
GO:0005886 IDA plasma membrane
GO:0005923 IDA tight junction
GO:0007165 IEA signal transduction
GO:0008285 ISS negative regulation of cell proliferation
GO:0010976 ISS positive regulation of neuron projection development
GO:0014069 ISS postsynaptic density
GO:0016482 ISS cytoplasmic transport
GO:0019902 IPI phosphatase binding
GO:0030159 IDA receptor signaling complex scaffold activity
GO:0030336 ISS negative regulation of cell migration
GO:0030425 ISS dendrite
GO:0031697 IPI beta-1 adrenergic receptor binding
GO:0032516 IDA positive regulation of phosphoprotein phosphatase activity
GO:0032926 ISS negative regulation of activin receptor signaling pathway
GO:0036057 ISS slit diaphragm
GO:0038180 ISS nerve growth factor signaling pathway
GO:0043113 ISS receptor clustering
GO:0043234 ISS protein complex
GO:0045202 ISS synapse
GO:0046332 ISS SMAD binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051291 ISS protein heterooligomerization
GO:0051898 IDA negative regulation of protein kinase B signaling
GO:0060395 ISS SMAD protein signal transduction
GO:0070699 ISS type II activin receptor binding
GO:0071850 ISS mitotic cell cycle arrest
GO:0072015 ISS glomerular visceral epithelial cell development
GO:1990090 ISS cellular response to nerve growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000088516 Magi2-003 protein_coding Mus_musculus 0 5526
ENSMUST00000115267 Magi2-002 protein_coding Mus_musculus 0 4606
ENSMUST00000101558 Magi2-001 protein_coding Mus_musculus 0 2752

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