C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenergic receptor kinase, beta 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000088737 Adrbk1-001 ENSMUSG00000024858 10090 - 19:4286002-4306222 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000088737
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000088737 9.297±4.46 9.573±2.46 16.204±3.78 12.693±0.34 23.207±5.36 17.468±5.47 12.192±2.53 8.359±2.36 7.233±4.31 12.791±4.19 18.183±1.90 8.273±4.06 13.373±5.02 2.118±0.80

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002026 IGI regulation of the force of heart contraction
GO:0002029 IMP desensitization of G-protein coupled receptor protein signaling pathway
GO:0003108 IEA negative regulation of the force of heart contraction by chemical signal
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004703 IDA G-protein coupled receptor kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006468 IDA protein phosphorylation
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007217 IEA tachykinin receptor signaling pathway
GO:0007507 IMP heart development
GO:0016020 IDA membrane
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0031623 IEA receptor internalization
GO:0031755 IEA Edg-2 lysophosphatidic acid receptor binding
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0045988 IEA negative regulation of striated muscle contraction
GO:0047696 IEA beta-adrenergic receptor kinase activity
GO:0060048 IEA cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000308595 ADRBK1-001 protein_coding Homo_sapiens 0 3066
ENST00000324198 ADRBK2-001 protein_coding Homo_sapiens 0 798
ENST00000416281 ADRBK1-002 retained_intron Homo_sapiens 0 1513
ENST00000524899 ADRBK1-007 processed_transcript Homo_sapiens 0 479
ENST00000526285 ADRBK1-011 protein_coding Homo_sapiens 0 1589
ENST00000526572 ADRBK1-014 retained_intron Homo_sapiens 0 580
ENST00000527176 ADRBK1-008 processed_transcript Homo_sapiens 0 977
ENST00000529815 ADRBK1-012 retained_intron Homo_sapiens 0 363
ENST00000532099 ADRBK1-006 processed_transcript Homo_sapiens 0 806
ENST00000532611 ADRBK1-009 retained_intron Homo_sapiens 0 291
ENST00000533077 ADRBK1-003 retained_intron Homo_sapiens 0 527
ENST00000534651 ADRBK1-013 retained_intron Homo_sapiens 0 401
ENST00000619906 ADRBK2-201 protein_coding Homo_sapiens 0 619

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