C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activin A receptor, type 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000090935 Acvr1-003 ENSMUSG00000026836 10090 - 2:58446441-58566826 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonLiverTestisENSMUST00000090935
Transcript ID Colon Liver Testis
ENSMUST00000090935 1.052±0.00 0.407±0.06 0.125±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000752 CIL_000752_0002 CGP 2:58267453-58567157

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0001569 IMP patterning of blood vessels
GO:0001655 IEA urogenital system development
GO:0001701 IMP in utero embryonic development
GO:0001702 IMP gastrulation with mouth forming second
GO:0001707 IMP mesoderm formation
GO:0001755 IMP neural crest cell migration
GO:0002526 IEP acute inflammatory response
GO:0003143 IEA embryonic heart tube morphogenesis
GO:0003183 IEA mitral valve morphogenesis
GO:0003289 IEA atrial septum primum morphogenesis
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0005025 IDA transforming growth factor beta receptor activity, type I
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 IDA integral component of plasma membrane
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007281 IMP germ cell development
GO:0007368 IMP determination of left/right symmetry
GO:0007369 IMP gastrulation
GO:0007498 IMP mesoderm development
GO:0007507 IMP heart development
GO:0009968 IEA negative regulation of signal transduction
GO:0010862 IEA positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016361 IDA activin receptor activity, type I
GO:0018107 IEA peptidyl-threonine phosphorylation
GO:0019838 IDA growth factor binding
GO:0030278 IEA regulation of ossification
GO:0030501 IEA positive regulation of bone mineralization
GO:0030509 IEA BMP signaling pathway
GO:0032924 IDA activin receptor signaling pathway
GO:0032926 IEA negative regulation of activin receptor signaling pathway
GO:0042803 IEA protein homodimerization activity
GO:0045177 IDA apical part of cell
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IEA SMAD binding
GO:0046872 IEA metal ion binding
GO:0048179 IEA activin receptor complex
GO:0048185 IPI activin binding
GO:0048641 IEA regulation of skeletal muscle tissue development
GO:0050431 IDA transforming growth factor beta binding
GO:0051145 IMP smooth muscle cell differentiation
GO:0060037 IMP pharyngeal system development
GO:0060389 IEA pathway-restricted SMAD protein phosphorylation
GO:0060923 IEA cardiac muscle cell fate commitment
GO:0061445 IEA endocardial cushion cell fate commitment
GO:0071385 IEA cellular response to glucocorticoid stimulus
GO:2000017 IEA positive regulation of determination of dorsal identity
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000027129 bmpr1ba-001 protein_coding Danio_rerio 1e-17 97
ENST00000263640 ACVR1-001 protein_coding Homo_sapiens 0 3186
ENST00000409283 ACVR1-003 protein_coding Homo_sapiens 0 3334
ENST00000410057 ACVR1-009 protein_coding Homo_sapiens 0 2204
ENST00000412025 ACVR1-007 protein_coding Homo_sapiens 0 355
ENST00000424669 ACVR1-004 protein_coding Homo_sapiens 0 285
ENST00000434821 ACVR1-201 protein_coding Homo_sapiens 0 3186
ENST00000440523 ACVR1-005 protein_coding Homo_sapiens 0 351
ENST00000487456 ACVR1-008 processed_transcript Homo_sapiens 0 599
ENST00000539637 ACVR1-002 protein_coding Homo_sapiens 0 291

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