C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rous sarcoma oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000092576 Src-201 ENSMUSG00000027646 10090 + 2:157424293-157471838 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLiverMuscleTestisENSMUST00000092576
Transcript ID Adrenal Brain Breast Colon Heart Liver Muscle Testis
ENSMUST00000092576 2.000±0.00 22.861±13.80 2.603±0.29 9.228±0.00 0.256±0.00 0.936±0.25 0.509±0.00 0.770±0.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YE CIL_0006YE_0002 CGP 2:157367594-157471862
CIL_0006Y4 CIL_0006Y4_0002 CGP 2:157418444-157571274

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004713 IMP protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005080 IEA protein kinase C binding
GO:0005102 IEA receptor binding
GO:0005158 IEA insulin receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005764 IEA lysosome
GO:0005770 IEA late endosome
GO:0005829 TAS cytosol
GO:0005884 IDA actin filament
GO:0005886 IDA plasma membrane
GO:0005901 IEA caveola
GO:0006468 IDA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0007173 IEA epidermal growth factor receptor signaling pathway
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008022 IEA protein C-terminus binding
GO:0008283 IEA cell proliferation
GO:0009612 IEA response to mechanical stimulus
GO:0009615 IEA response to virus
GO:0010447 IEA response to acidity
GO:0010628 IEA positive regulation of gene expression
GO:0010632 IEA regulation of epithelial cell migration
GO:0010641 IEA positive regulation of platelet-derived growth factor receptor signaling pathway
GO:0010907 IEA positive regulation of glucose metabolic process
GO:0014069 IEA postsynaptic density
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0016301 IMP kinase activity
GO:0016337 IEA single organismal cell-cell adhesion
GO:0016477 IMP cell migration
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019899 IEA enzyme binding
GO:0019901 IEA protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0020037 ISS heme binding
GO:0022407 IEA regulation of cell-cell adhesion
GO:0030331 IEA estrogen receptor binding
GO:0030900 IGI forebrain development
GO:0031667 IEA response to nutrient levels
GO:0031954 IEA positive regulation of protein autophosphorylation
GO:0032148 IEA activation of protein kinase B activity
GO:0032403 IEA protein complex binding
GO:0032463 IEA negative regulation of protein homooligomerization
GO:0032587 IDA ruffle membrane
GO:0032869 IEA cellular response to insulin stimulus
GO:0033146 IMP regulation of intracellular estrogen receptor signaling pathway
GO:0034332 IEA adherens junction organization
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0035556 IGI intracellular signal transduction
GO:0036035 IGI osteoclast development
GO:0036120 IDA cellular response to platelet-derived growth factor stimulus
GO:0042169 IEA SH2 domain binding
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0043005 IEA neuron projection
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043149 IEA stress fiber assembly
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043393 IDA regulation of protein binding
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0043552 IEA positive regulation of phosphatidylinositol 3-kinase activity
GO:0044325 IEA ion channel binding
GO:0045056 IEA transcytosis
GO:0045453 IMP bone resorption
GO:0045737 IEA positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045785 IEA positive regulation of cell adhesion
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046628 IEA positive regulation of insulin receptor signaling pathway
GO:0046777 IEA protein autophosphorylation
GO:0046875 IPI ephrin receptor binding
GO:0048011 IEA neurotrophin TRK receptor signaling pathway
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048477 IMP oogenesis
GO:0050715 IEA positive regulation of cytokine secretion
GO:0050839 IEA cell adhesion molecule binding
GO:0050847 IEA progesterone receptor signaling pathway
GO:0051219 IEA phosphoprotein binding
GO:0051222 IEA positive regulation of protein transport
GO:0051385 IEA response to mineralocorticoid
GO:0051602 IEA response to electrical stimulus
GO:0051895 IEA negative regulation of focal adhesion assembly
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0051902 IEA negative regulation of mitochondrial depolarization
GO:0060065 IMP uterus development
GO:0060444 IMP branching involved in mammary gland duct morphogenesis
GO:0060491 IGI regulation of cell projection assembly
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0070542 IEA response to fatty acid
GO:0070555 IEA response to interleukin-1
GO:0070851 IEA growth factor receptor binding
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071393 IEA cellular response to progesterone stimulus
GO:0071398 IEA cellular response to fatty acid
GO:0071456 IEA cellular response to hypoxia
GO:0071803 IDA positive regulation of podosome assembly
GO:0090263 IGI positive regulation of canonical Wnt signaling pathway
GO:1902533 IEA positive regulation of intracellular signal transduction
GO:2000573 IEA positive regulation of DNA biosynthetic process
GO:2000641 IEA regulation of early endosome to late endosome transport
GO:2000811 IEA negative regulation of anoikis
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway
GO:2001243 IEA negative regulation of intrinsic apoptotic signaling pathway
GO:2001286 IEA regulation of caveolin-mediated endocytosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000036635 fynb-001 protein_coding Danio_rerio 0 508
ENST00000358208 SRC-201 protein_coding Homo_sapiens 0 2073
ENST00000373558 SRC-005 protein_coding Homo_sapiens 0 2128
ENST00000373567 SRC-002 protein_coding Homo_sapiens 0 2015
ENST00000373578 SRC-001 protein_coding Homo_sapiens 0 2071
ENST00000472968 SRC-003 processed_transcript Homo_sapiens 0 333
ENST00000477066 SRC-004 processed_transcript Homo_sapiens 0 1147
ENST00000489153 SRC-006 processed_transcript Homo_sapiens 0 562
ENST00000493775 SRC-009 processed_transcript Homo_sapiens 0 342

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