C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: delta-like 4 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102517 Dll4-001 ENSMUSG00000027314 10090 + 2:119325784-119335962 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102517
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102517 16.493±7.17 7.184±1.83 2.649±0.24 1.738±1.03 6.765±2.80 7.183±0.46 6.687±0.85 4.824±0.69 1.100±0.29 37.348±11.00 2.015±0.34 6.935±2.17 2.012±0.52 0.223±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000799 CIL_000799_0002 CGP 2:119288740-119335962
CIL_0005IN CIL_0005IN_0003 CGP 2:119325784-119354381

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001525 IMP angiogenesis
GO:0001569 IMP patterning of blood vessels
GO:0001974 IMP blood vessel remodeling
GO:0003208 IMP cardiac ventricle morphogenesis
GO:0003209 IMP cardiac atrium morphogenesis
GO:0003222 IMP ventricular trabecula myocardium morphogenesis
GO:0003344 IMP pericardium morphogenesis
GO:0005112 IDA Notch binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007601 IEA visual perception
GO:0008285 ISS negative regulation of cell proliferation
GO:0010596 ISS negative regulation of endothelial cell migration
GO:0035912 IMP dorsal aorta morphogenesis
GO:0035924 ISS cellular response to vascular endothelial growth factor stimulus
GO:0043537 IDA negative regulation of blood vessel endothelial cell migration
GO:0044344 ISS cellular response to fibroblast growth factor stimulus
GO:0050767 IMP regulation of neurogenesis
GO:0060579 ISS ventral spinal cord interneuron fate commitment
GO:0061074 IMP regulation of neural retina development
GO:0061314 IMP Notch signaling involved in heart development
GO:0072554 IMP blood vessel lumenization
GO:0090051 ISS negative regulation of cell migration involved in sprouting angiogenesis
GO:2000179 IMP positive regulation of neural precursor cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000249749 DLL4-001 protein_coding Homo_sapiens 0 2470
ENST00000557876 DLL4-002 retained_intron Homo_sapiens 0 481
ENST00000559440 DLL4-003 retained_intron Homo_sapiens 0 660

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