C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glucokinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102920 Gck-004 ENSMUSG00000041798 10090 - 11:5900823-5950081 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainColonLiverLungOvaryPlacentaTestisENSMUST00000102920
Transcript ID Adipose Adrenal Brain Colon Liver Lung Ovary Placenta Testis
ENSMUST00000102920 0.075±0.02 0.295±0.15 0.695±0.09 0.156±0.02 0.023±0.01 0.390±0.10 0.668±0.35 0.015±0.00 2.690±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006I9 CIL_0006I9_0003 CGP 11:5896637-5950081
CIL_0000J5 CIL_0000J5_0002 CGP 11:5900820-5967780

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001678 IMP cellular glucose homeostasis
GO:0004340 ISS glucokinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005536 ISS glucose binding
GO:0005634 IDA nucleus
GO:0005654 IEA nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IBA cytosol
GO:0005884 IEA actin filament
GO:0005938 IEA cell cortex
GO:0005978 IEA glycogen biosynthetic process
GO:0006003 IEA fructose 2,6-bisphosphate metabolic process
GO:0006006 IDA glucose metabolic process
GO:0006096 IBA glycolytic process
GO:0006739 IMP NADP metabolic process
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0009749 IEA response to glucose
GO:0019903 IEA protein phosphatase binding
GO:0019932 IEA second-messenger-mediated signaling
GO:0030141 IEA secretory granule
GO:0031018 TAS endocrine pancreas development
GO:0032024 ISS positive regulation of insulin secretion
GO:0032811 IEA negative regulation of epinephrine secretion
GO:0032869 IEA cellular response to insulin stimulus
GO:0042149 IEA cellular response to glucose starvation
GO:0042327 IEA positive regulation of phosphorylation
GO:0042593 ISS glucose homeostasis
GO:0043266 IMP regulation of potassium ion transport
GO:0043531 IEA ADP binding
GO:0044320 IEA cellular response to leptin stimulus
GO:0045180 IEA basal cortex
GO:0045721 ISS negative regulation of gluconeogenesis
GO:0045725 ISS positive regulation of glycogen biosynthetic process
GO:0045821 IEA positive regulation of glycolytic process
GO:0046835 IDA carbohydrate phosphorylation
GO:0050796 IMP regulation of insulin secretion
GO:0051156 IEA glucose 6-phosphate metabolic process
GO:0051594 ISS detection of glucose
GO:0055088 IEA lipid homeostasis
GO:0070509 IMP calcium ion import

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000336642 GCK-006 protein_coding Homo_sapiens 0 407
ENST00000345378 GCK-002 protein_coding Homo_sapiens 0 1670
ENST00000395796 GCK-003 protein_coding Homo_sapiens 0 1672
ENST00000403799 GCK-001 protein_coding Homo_sapiens 0 1779
ENST00000437084 GCK-004 protein_coding Homo_sapiens 0 1155
ENST00000459642 GCK-005 retained_intron Homo_sapiens 0 411
ENST00000476008 GCK-008 processed_transcript Homo_sapiens 7e-27 124
ENST00000616242 GCK-201 protein_coding Homo_sapiens 0 1672

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