C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GATA binding protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000102976 Gata3-001 ENSMUSG00000015619 10090 - 2:9857078-9878600 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000102976
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000102976 0.361±0.19 7.023±0.20 33.508±2.58 4.090±4.66 19.929±14.87 0.360±0.09 0.093±0.03 4.823±1.01 0.173±0.10 3.456±0.25 0.082±0.02 0.387±0.18 9.200±4.90

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003RS CIL_0003RS_0002 CGP 2:6539694-9890034
CIL_0007J5 CIL_0007J5_0002 UCNEbase 2:9433268-9958392

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000902 IMP cell morphogenesis
GO:0000976 IEA transcription regulatory region sequence-specific DNA binding
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 ISS core promoter proximal region sequence-specific DNA binding
GO:0001046 IEA core promoter sequence-specific DNA binding
GO:0001071 IEA nucleic acid binding transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001701 IMP in utero embryonic development
GO:0001709 IDA cell fate determination
GO:0001764 IMP neuron migration
GO:0001775 IMP cell activation
GO:0001806 IEA type IV hypersensitivity
GO:0001819 IDA positive regulation of cytokine production
GO:0001822 IEA kidney development
GO:0001823 IMP mesonephros development
GO:0002088 IMP lens development in camera-type eye
GO:0002572 IMP pro-T cell differentiation
GO:0003180 IMP aortic valve morphogenesis
GO:0003215 IMP cardiac right ventricle morphogenesis
GO:0003281 IMP ventricular septum development
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003713 IDA:ISS transcription coactivator activity
GO:0005134 IPI interleukin-2 receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0006959 IMP humoral immune response
GO:0007165 IMP signal transduction
GO:0007399 IMP nervous system development
GO:0007411 IMP axon guidance
GO:0008134 IEA transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0008584 IMP male gonad development
GO:0009615 IEA response to virus
GO:0009791 IMP post-embryonic development
GO:0009967 ISS positive regulation of signal transduction
GO:0010332 IEA response to gamma radiation
GO:0010595 ISS positive regulation of endothelial cell migration
GO:0010629 IMP negative regulation of gene expression
GO:0010975 IMP regulation of neuron projection development
GO:0014065 IMP phosphatidylinositol 3-kinase signaling
GO:0030182 IMP neuron differentiation
GO:0030217 IDA T cell differentiation
GO:0030218 IDA erythrocyte differentiation
GO:0031929 IMP TOR signaling
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032703 IDA negative regulation of interleukin-2 production
GO:0032736 IMP positive regulation of interleukin-13 production
GO:0032753 IMP positive regulation of interleukin-4 production
GO:0032754 IMP positive regulation of interleukin-5 production
GO:0033077 IMP T cell differentiation in thymus
GO:0033600 IEA negative regulation of mammary gland epithelial cell proliferation
GO:0035162 IGI embryonic hemopoiesis
GO:0035457 IEA cellular response to interferon-alpha
GO:0035799 IMP ureter maturation
GO:0035898 IMP parathyroid hormone secretion
GO:0042035 IDA regulation of cytokine biosynthetic process
GO:0042421 IMP norepinephrine biosynthetic process
GO:0042472 IMP inner ear morphogenesis
GO:0042493 IEA response to drug
GO:0043370 IMP regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043523 IMP regulation of neuron apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0043583 ISS ear development
GO:0043627 IEA response to estrogen
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045061 IMP thymic T cell selection
GO:0045064 IDA T-helper 2 cell differentiation
GO:0045087 IEA innate immune response
GO:0045471 IEA response to ethanol
GO:0045582 IEA:IDA positive regulation of T cell differentiation
GO:0045597 IMP positive regulation of cell differentiation
GO:0045599 ISS negative regulation of fat cell differentiation
GO:0045786 IMP:ISS negative regulation of cell cycle
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IDA protein dimerization activity
GO:0048469 IMP cell maturation
GO:0048485 IMP sympathetic nervous system development
GO:0048538 IMP thymus development
GO:0048568 IMP embryonic organ development
GO:0048589 IMP developmental growth
GO:0048646 IMP anatomical structure formation involved in morphogenesis
GO:0048872 IMP homeostasis of number of cells
GO:0050728 ISS negative regulation of inflammatory response
GO:0050852 IDA T cell receptor signaling pathway
GO:0051569 IDA regulation of histone H3-K4 methylation
GO:0051897 ISS positive regulation of protein kinase B signaling
GO:0060017 IMP parathyroid gland development
GO:0060037 IMP pharyngeal system development
GO:0060065 IMP uterus development
GO:0060231 ISS mesenchymal to epithelial transition
GO:0060374 IDA mast cell differentiation
GO:0060676 IMP ureteric bud formation
GO:0061085 IDA regulation of histone H3-K27 methylation
GO:0061290 IMP canonical Wnt signaling pathway involved in metanephric kidney development
GO:0070888 ISS E-box binding
GO:0071345 IDA cellular response to cytokine stimulus
GO:0071353 IDA cellular response to interleukin-4
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071599 IMP otic vesicle development
GO:0071773 IDA cellular response to BMP stimulus
GO:0071837 IEA HMG box domain binding
GO:0072001 IGI renal system development
GO:0072107 IMP positive regulation of ureteric bud formation
GO:0072178 IMP nephric duct morphogenesis
GO:0072179 IMP nephric duct formation
GO:0072182 IMP regulation of nephron tubule epithelial cell differentiation
GO:0072602 IMP interleukin-4 secretion
GO:0072643 IMP interferon-gamma secretion
GO:0072676 ISS lymphocyte migration
GO:2000114 IDA regulation of establishment of cell polarity
GO:2000146 ISS negative regulation of cell motility
GO:2000352 ISS negative regulation of endothelial cell apoptotic process
GO:2000607 IMP negative regulation of cell proliferation involved in mesonephros development
GO:2000611 ISS positive regulation of thyroid hormone generation
GO:2000664 ISS positive regulation of interleukin-5 secretion
GO:2000667 ISS positive regulation of interleukin-13 secretion
GO:2000679 IMP positive regulation of transcription regulatory region DNA binding
GO:2000683 ISS regulation of cellular response to X-ray
GO:2000703 IMP negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation
GO:2000734 IMP negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000346208 GATA3-002 protein_coding Homo_sapiens 0 2146
ENST00000379328 GATA3-001 protein_coding Homo_sapiens 0 2165
ENST00000461472 GATA3-004 processed_transcript Homo_sapiens 0 571

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