C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DOT1-like, histone H3 methyltransferase (S. cerevisiae)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000105336 Dot1l-001 ENSMUSG00000061589 10090 + 10:80755206-80795461 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000105336
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000105336 5.041±1.59 11.664±5.19 4.119±2.21 8.815±3.59 2.615±1.96 4.218±2.39 4.848±2.03 2.741±1.03 3.600±2.82 4.152±0.71 6.825±0.78 5.751±4.46 12.569±7.79 18.525±6.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009C CIL_00009C_0002 CGP 10:80706978-80795461
CIL_0001T8 CIL_0001T8_0002 CGP 10:80755206-80798626

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0008134 IEA transcription factor binding
GO:0016571 IDA histone methylation
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0034968 IEA histone lysine methylation
GO:0042054 IDA histone methyltransferase activity
GO:0046425 IEA regulation of JAK-STAT cascade
GO:2000677 IEA regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000089076 dot1l-201 protein_coding Danio_rerio 0 856
ENSDART00000142046 dot1l-001 protein_coding Danio_rerio 0 828
ENST00000398665 DOT1L-001 protein_coding Homo_sapiens 0 4047
ENST00000452696 DOT1L-003 protein_coding Homo_sapiens 0 451
ENST00000457590 DOT1L-008 protein_coding Homo_sapiens 0 983
ENST00000478937 DOT1L-004 nonsense_mediated_decay Homo_sapiens 0 368
ENST00000482433 DOT1L-002 retained_intron Homo_sapiens 0 660
ENST00000608122 DOT1L-006 processed_transcript Homo_sapiens 0 459

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