C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SPEN homolog, transcriptional regulator (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000105786 Spen-001 ENSMUSG00000040761 10090 - 4:141467890-141538597 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000105786
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000105786 0.863±0.00 1.449±0.30 1.210±0.00 1.627±0.08 4.334±0.97 0.782±0.00 2.244±1.16 0.611±0.13 1.160±0.04 0.705±0.00 2.475±0.67 1.733±0.91 2.299±0.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QM CIL_0007QM_0002 VISTA 4:141236761-141837859

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000166 IEA nucleotide binding
GO:0001085 IEA RNA polymerase II transcription factor binding
GO:0001191 IEA RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0003697 IDA single-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0017053 IEA transcriptional repressor complex
GO:0044822 IEA poly(A) RNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0050769 IEA positive regulation of neurogenesis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000261712 PSMD11-001 protein_coding Homo_sapiens 0.00002 57
ENST00000375759 SPEN-001 protein_coding Homo_sapiens 0 2713
ENST00000438066 SPEN-002 protein_coding Homo_sapiens 0 1026
ENST00000442985 SPEN-004 protein_coding Homo_sapiens 0 983
ENST00000457654 PSMD11-004 protein_coding Homo_sapiens 0.00001 57
ENST00000471538 SPEN-003 processed_transcript Homo_sapiens 0 695
ENST00000487496 SPEN-005 processed_transcript Homo_sapiens 0 455

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