C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphodiesterase 4B, cAMP specific
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000106911 Pde4b-003 ENSMUSG00000028525 10090 + 4:102087543-102605833 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NS CIL_0002NS_0002 CGP 4:102087543-102973628

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001780 IMP neutrophil homeostasis
GO:0004114 IDA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 ISS 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006198 IDA cAMP catabolic process
GO:0007165 IEA signal transduction
GO:0008152 IEA metabolic process
GO:0030018 IMP Z disc
GO:0030593 IMP neutrophil chemotaxis
GO:0035690 IDA cellular response to drug
GO:0044325 IPI ion channel binding
GO:0046872 IEA metal ion binding
GO:0050900 IMP leukocyte migration
GO:0071222 IMP cellular response to lipopolysaccharide
GO:0071872 IMP cellular response to epinephrine stimulus
GO:0071944 IDA cell periphery
GO:0086004 IMP regulation of cardiac muscle cell contraction
GO:1901841 IMP regulation of high voltage-gated calcium channel activity
GO:1901898 IMP negative regulation of relaxation of cardiac muscle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000329654 PDE4B-001 protein_coding Homo_sapiens 0 3103
ENST00000341517 PDE4B-002 protein_coding Homo_sapiens 0 3103
ENST00000371045 PDE4B-007 protein_coding Homo_sapiens 0 2329
ENST00000423207 PDE4B-003 protein_coding Homo_sapiens 0 2741
ENST00000480109 PDE4B-008 protein_coding Homo_sapiens 0 1943
ENST00000483863 PDE4B-018 retained_intron Homo_sapiens 0 329
ENST00000524999 PDE4B-016 processed_transcript Homo_sapiens 0 322
ENST00000526197 PDE4B-011 protein_coding Homo_sapiens 0 638
ENST00000528771 PDE4B-009 protein_coding Homo_sapiens 0 608
ENST00000531025 PDE4B-010 protein_coding Homo_sapiens 0 604
ENST00000532040 PDE4B-012 processed_transcript Homo_sapiens 7e-27 124
ENST00000534463 PDE4B-015 retained_intron Homo_sapiens 0 630

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