C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Kruppel-like factor 4 (gut)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107619 Klf4-001 ENSMUSG00000003032 10090 - 4:55527143-55532466 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000107619
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107619 15.088±2.14 5.467±1.03 26.407±0.23 0.912±0.51 16.905±7.54 162.562±41.67 7.912±2.16 3.007±0.70 0.447±0.25 35.087±3.61 4.446±0.68 5.971±2.48 9.815±9.11 34.769±18.68

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000225 CIL_000225_0003 CGP 4:55350043-55532466
CIL_0001JU CIL_0001JU_0002 CGP 4:55527143-56741443

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IEA chromatin
GO:0000790 IEA nuclear chromatin
GO:0000987 IEA core promoter proximal region sequence-specific DNA binding
GO:0001010 IDA sequence-specific DNA binding transcription factor recruiting transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001221 IEA transcription cofactor binding
GO:0003677 ISS DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0008134 IPI transcription factor binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0009913 IMP epidermal cell differentiation
GO:0010033 IDA response to organic substance
GO:0014067 IEA negative regulation of phosphatidylinositol 3-kinase signaling
GO:0014740 IEA negative regulation of muscle hyperplasia
GO:0019827 IDA stem cell maintenance
GO:0030154 IMP cell differentiation
GO:0031077 IMP post-embryonic camera-type eye development
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0032270 IEA positive regulation of cellular protein metabolic process
GO:0032526 IDA response to retinoic acid
GO:0034115 IEA negative regulation of heterotypic cell-cell adhesion
GO:0035014 IEA phosphatidylinositol 3-kinase regulator activity
GO:0035166 IEA post-embryonic hemopoiesis
GO:0042127 IGI regulation of cell proliferation
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045415 IEA negative regulation of interleukin-8 biosynthetic process
GO:0045429 IEA positive regulation of nitric oxide biosynthetic process
GO:0045444 IMP fat cell differentiation
GO:0045595 IDA regulation of cell differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0046985 IEA positive regulation of hemoglobin biosynthetic process
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0048730 IMP epidermis morphogenesis
GO:0051247 IEA positive regulation of protein metabolic process
GO:0051898 IEA negative regulation of protein kinase B signaling
GO:0060761 IEA negative regulation of response to cytokine stimulus
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0070373 IEA negative regulation of ERK1 and ERK2 cascade
GO:0071363 IEA cellular response to growth factor stimulus
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071409 IEA cellular response to cycloheximide
GO:0071499 IEA cellular response to laminar fluid shear stress
GO:0090051 IEA negative regulation of cell migration involved in sprouting angiogenesis
GO:1901653 IEA cellular response to peptide
GO:2000342 IEA negative regulation of chemokine (C-X-C motif) ligand 2 production

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000374672 KLF4-002 protein_coding Homo_sapiens 0 2176
ENST00000411706 KLF4-004 protein_coding Homo_sapiens 0 848
ENST00000420475 KLF4-006 protein_coding Homo_sapiens 0 429
ENST00000493306 KLF4-003 retained_intron Homo_sapiens 0 1378
ENST00000497048 KLF4-001 retained_intron Homo_sapiens 0 1598
ENST00000610832 KLF4-201 protein_coding Homo_sapiens 0 894

Loading