C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: MKL (megakaryoblastic leukemia)/myocardin-like 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000109579 Mkl1-002 ENSMUSG00000042292 10090 - 15:81012291-81105083 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastHeartKidneyLungMuscleOvaryPlacentaENSMUST00000109579
Transcript ID Bladder Brain Breast Heart Kidney Lung Muscle Ovary Placenta
ENSMUST00000109579 3.631±0.00 10.570±0.00 4.646±2.68 0.949±0.00 1.492±0.30 4.290±0.00 1.533±0.00 3.124±1.01 4.854±2.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005W1 CIL_0005W1_0002 CGP 15:80977765-81190757
CIL_0005W2 CIL_0005W2_0002 CGP 15:81012281-81238963

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0003779 IDA actin binding
GO:0003785 IDA actin monomer binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0010735 ISS positive regulation of transcription via serum response element binding
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043522 IEA leucine zipper domain binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051145 IEA smooth muscle cell differentiation
GO:2001234 IDA negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000355630 MKL1-001 protein_coding Homo_sapiens 0 2795
ENST00000396617 MKL1-201 protein_coding Homo_sapiens 0 2754
ENST00000402042 MKL1-002 protein_coding Homo_sapiens 0 1962
ENST00000402630 MKL1-009 protein_coding Homo_sapiens 0 516
ENST00000407029 MKL1-003 protein_coding Homo_sapiens 0 2798
ENST00000422851 MKL1-006 protein_coding Homo_sapiens 0 274
ENST00000614754 MKL1-202 protein_coding Homo_sapiens 0 2654
ENST00000618196 MKL1-203 protein_coding Homo_sapiens 0 2863
ENST00000618417 MKL1-204 protein_coding Homo_sapiens 0 553
ENST00000620651 MKL1-205 protein_coding Homo_sapiens 0 1962

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