C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glucokinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000109823 Gck-001 ENSMUSG00000041798 10090 - 11:5900820-5915124 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000109823
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000109823 0.013±0.00 0.749±0.60 0.024±0.01 1.072±0.00 0.261±0.09 0.247±0.12 3.630±1.06 0.081±0.03 33.110±33.99 0.293±0.20 3.569±1.49 0.724±0.47 0.149±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006I9 CIL_0006I9_0003 CGP 11:5896637-5950081
CIL_0000J5 CIL_0000J5_0002 CGP 11:5900820-5967780

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001678 IMP cellular glucose homeostasis
GO:0004340 ISS glucokinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS ATP binding
GO:0005536 ISS glucose binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005829 IBA cytosol
GO:0006006 IDA glucose metabolic process
GO:0006096 IBA glycolytic process
GO:0006739 IMP NADP metabolic process
GO:0031018 TAS endocrine pancreas development
GO:0032024 ISS positive regulation of insulin secretion
GO:0042593 ISS glucose homeostasis
GO:0043266 IMP regulation of potassium ion transport
GO:0045721 ISS negative regulation of gluconeogenesis
GO:0045725 ISS positive regulation of glycogen biosynthetic process
GO:0046835 IDA carbohydrate phosphorylation
GO:0050796 IMP regulation of insulin secretion
GO:0051594 ISS detection of glucose
GO:0070509 IMP calcium ion import

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000336642 GCK-006 protein_coding Homo_sapiens 0 407
ENST00000345378 GCK-002 protein_coding Homo_sapiens 0 1685
ENST00000395796 GCK-003 protein_coding Homo_sapiens 0 1670
ENST00000403799 GCK-001 protein_coding Homo_sapiens 0 1670
ENST00000437084 GCK-004 protein_coding Homo_sapiens 0 1155
ENST00000459642 GCK-005 retained_intron Homo_sapiens 0 411
ENST00000476008 GCK-008 processed_transcript Homo_sapiens 7e-27 124
ENST00000616242 GCK-201 protein_coding Homo_sapiens 0 1670

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