C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000110998 Map2k7-001 ENSMUSG00000002948 10090 + 8:4238740-4247896 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000110998
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000110998 7.069±1.71 13.898±1.55 7.090±1.42 24.061±2.00 8.180±2.37 10.496±2.47 3.132±0.26 9.239±1.91 9.357±1.06 10.778±2.03 14.064±3.32 8.112±0.92 11.605±1.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002FU CIL_0002FU_0002 CGP 8:4226827-4251423
CIL_0002FR CIL_0002FR_0002 CGP 8:4238740-4251423

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 IDA MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006915 IEA apoptotic process
GO:0006950 IDA response to stress
GO:0007257 IDA activation of JUN kinase activity
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019903 IPI protein phosphatase binding
GO:0051403 IDA stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000397979 MAP2K7-002 protein_coding Homo_sapiens 0 1845
ENST00000397981 MAP2K7-001 protein_coding Homo_sapiens 0 1821
ENST00000397983 MAP2K7-003 protein_coding Homo_sapiens 0 1589
ENST00000468058 MAP2K7-004 retained_intron Homo_sapiens 0 1275
ENST00000475022 MAP2K7-005 retained_intron Homo_sapiens 0 237
ENST00000494348 MAP2K7-008 retained_intron Homo_sapiens 0 222

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