C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000111945 Mapk8-001 ENSMUSG00000021936 10090 - 14:33377898-33447158 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastLiverMuscleOvaryPlacentaTestisENSMUST00000111945
Transcript ID Adipose Bladder Brain Breast Liver Muscle Ovary Placenta Testis
ENSMUST00000111945 0.834±0.56 0.543±0.00 14.258±5.91 1.196±0.39 1.581±0.90 0.860±0.26 1.622±0.00 1.601±0.74 0.569±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006H2 CIL_0006H2_0003 CGP 14:33214026-33447158
CIL_0007BW CIL_0007BW_0003 CGP 14:33377898-33640754

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001503 IMP ossification
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004705 IDA JUN kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IDA cytosol
GO:0006468 IDA protein phosphorylation
GO:0007254 IDA JNK cascade
GO:0007258 IMP JUN phosphorylation
GO:0009411 IEA response to UV
GO:0010468 IMP regulation of gene expression
GO:0010628 IEA positive regulation of gene expression
GO:0016301 IDA kinase activity
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0018107 IMP peptidyl-threonine phosphorylation
GO:0031063 IEA regulation of histone deacetylation
GO:0032091 IEA negative regulation of protein binding
GO:0032880 IEA regulation of protein localization
GO:0035033 IEA histone deacetylase regulator activity
GO:0042826 IEA histone deacetylase binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0046686 IGI response to cadmium ion
GO:0048263 ISO determination of dorsal identity
GO:0070301 IDA cellular response to hydrogen peroxide
GO:0071222 ISO cellular response to lipopolysaccharide
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071732 IMP cellular response to nitric oxide
GO:0090045 IEA positive regulation of deacetylase activity
GO:0097300 IMP programmed necrotic cell death
GO:2000017 IDA positive regulation of determination of dorsal identity
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000132129 mapk8a-002 protein_coding Danio_rerio 0 719
ENST00000343111 MAPK9-002 protein_coding Homo_sapiens 0 673
ENST00000359221 MAPK10-012 protein_coding Homo_sapiens 0 880
ENST00000360332 MAPK8-201 protein_coding Homo_sapiens 0 2161
ENST00000361569 MAPK10-005 protein_coding Homo_sapiens 0 905
ENST00000374174 MAPK8-013 protein_coding Homo_sapiens 0 972
ENST00000374176 MAPK8-014 protein_coding Homo_sapiens 0 3343
ENST00000374179 MAPK8-012 protein_coding Homo_sapiens 0 3380
ENST00000374182 MAPK8-011 protein_coding Homo_sapiens 0 3524
ENST00000374189 MAPK8-006 protein_coding Homo_sapiens 0 3609
ENST00000393360 MAPK9-003 protein_coding Homo_sapiens 0 595
ENST00000393362 MAPK9-007 nonsense_mediated_decay Homo_sapiens 0 405
ENST00000395157 MAPK10-014 protein_coding Homo_sapiens 0 675
ENST00000395160 MAPK10-004 protein_coding Homo_sapiens 0 701
ENST00000395166 MAPK10-002 protein_coding Homo_sapiens 0 880
ENST00000395169 MAPK10-001 protein_coding Homo_sapiens 0 880
ENST00000395611 MAPK8-202 protein_coding Homo_sapiens 0 3483
ENST00000397072 MAPK9-201 protein_coding Homo_sapiens 0 518
ENST00000426557 MAPK8-009 protein_coding Homo_sapiens 0 767
ENST00000429041 MAPK8-004 protein_coding Homo_sapiens 0 475
ENST00000432379 MAPK8-008 protein_coding Homo_sapiens 0 771
ENST00000452135 MAPK9-001 protein_coding Homo_sapiens 0 577
ENST00000455781 MAPK9-004 protein_coding Homo_sapiens 0 654
ENST00000459755 MAPK8-002 processed_transcript Homo_sapiens 0 1273
ENST00000469110 MAPK8-001 retained_intron Homo_sapiens 0 1844
ENST00000469879 MAPK8-005 processed_transcript Homo_sapiens 0 664
ENST00000471272 MAPK8-003 retained_intron Homo_sapiens 0 555
ENST00000476134 MAPK8-010 processed_transcript Homo_sapiens 0 808
ENST00000482840 MAPK8-007 processed_transcript Homo_sapiens 0 462
ENST00000508262 MAPK10-016 retained_intron Homo_sapiens 0 401
ENST00000520212 MAPK9-010 retained_intron Homo_sapiens 0 224
ENST00000524170 MAPK9-011 processed_transcript Homo_sapiens 0 231

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