C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: p21 protein (Cdc42/Rac)-activated kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112863 Pak3-001 ENSMUSG00000031284 10090 + X:143665745-143797792 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079V CIL_00079V_0002 CGP X:143285674-143797796
CIL_00079U CIL_00079U_0002 CGP X:143518591-143827414

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000187 IEA activation of MAPK activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 ISS MAP kinase kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0006468 IEA protein phosphorylation
GO:0007409 IMP axonogenesis
GO:0010975 IEA regulation of neuron projection development
GO:0016358 IMP dendrite development
GO:0017048 IPI Rho GTPase binding
GO:0017124 IEA SH3 domain binding
GO:0030833 ISS regulation of actin filament polymerization
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0046872 IEA metal ion binding
GO:0051020 IEA GTPase binding
GO:0061003 IEA positive regulation of dendritic spine morphogenesis
GO:2000573 IEA positive regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000098417 pak2a-201 protein_coding Danio_rerio 0 540
ENST00000262836 PAK3-201 protein_coding Homo_sapiens 0 3079
ENST00000360648 PAK3-202 protein_coding Homo_sapiens 0 2614
ENST00000372007 PAK3-001 protein_coding Homo_sapiens 0 3105
ENST00000372010 PAK3-002 protein_coding Homo_sapiens 0 3096
ENST00000417227 PAK3-203 protein_coding Homo_sapiens 0 2891
ENST00000425146 PAK3-204 protein_coding Homo_sapiens 0 2531
ENST00000429193 PAK3-003 protein_coding Homo_sapiens 0 468
ENST00000446737 PAK3-205 protein_coding Homo_sapiens 0 2531
ENST00000484442 PAK3-004 processed_transcript Homo_sapiens 9e-32 141
ENST00000487802 PAK3-005 processed_transcript Homo_sapiens 0 268
ENST00000518291 PAK3-007 protein_coding Homo_sapiens 0 1977
ENST00000519681 PAK3-006 protein_coding Homo_sapiens 0 2915
ENST00000620137 PAK3-206 protein_coding Homo_sapiens 0 2551

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