C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: p21 protein (Cdc42/Rac)-activated kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372007 PAK3-001 ENSG00000077264 9606 + X:111096377-111227361 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartLiverLungMuscleOvaryPlacentaTestisENST00000372007
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000372007 0.098±0.00 0.131±0.00 0.014±0.00 1.592±0.00 0.411±0.00 0.031±0.00 0.092±0.00 0.131±0.03 0.011±0.00 0.174±0.17 0.037±0.01 1.029±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079V CIL_00079V_0001 CGP X:110673856-111227361
CIL_00079U CIL_00079U_0001 CGP X:110944285-111270523

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IDA MAPK cascade
GO:0000187 IDA activation of MAPK activity
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 IDA MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0007015 IEA actin filament organization
GO:0007409 ISS axonogenesis
GO:0016358 ISS dendrite development
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017124 IEA SH3 domain binding
GO:0030833 IDA regulation of actin filament polymerization
GO:0046872 IEA metal ion binding
GO:0050808 TAS synapse organization
GO:0060997 TAS dendritic spine morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112865 Pak3-004 protein_coding Mus_musculus 0 3882
ENSMUST00000112868 Pak3-005 protein_coding Mus_musculus 0 3574
ENSMUST00000112864 Pak3-002 protein_coding Mus_musculus 0 3574
ENSMUST00000172330 Pak3-201 protein_coding Mus_musculus 0 3572
ENSMUST00000033640 Pak3-008 protein_coding Mus_musculus 0 3105
ENSMUST00000112863 Pak3-001 protein_coding Mus_musculus 0 3105
ENSMUST00000134402 Pak3-009 protein_coding Mus_musculus 0 937
ENSMUST00000156449 Pak3-006 protein_coding Mus_musculus 0 737
ENSMUST00000023467 Pak2-001 protein_coding Mus_musculus 0 531
ENSMUST00000155215 Pak3-007 protein_coding Mus_musculus 0 470
ENSDART00000009560 pak1-201 protein_coding Danio_rerio 0 233
ENSMUST00000126592 Pak3-003 protein_coding Mus_musculus 7e-38 165

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