C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: disabled 2 interacting protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112986 Dab2ip-003 ENSMUSG00000026883 10090 + 2:35558266-35730994 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; MuscleENSMUST00000112986
Transcript ID Muscle
ENSMUST00000112986 2.428±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006N4 CIL_0006N4_0002 CGP 2:35558266-35979913

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000185 ISS activation of MAPKKK activity
GO:0001525 IEA angiogenesis
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0005099 IBA Ras GTPase activator activity
GO:0005515 IPI protein binding
GO:0005737 IBA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006954 IEA inflammatory response
GO:0006986 IEA response to unfolded protein
GO:0007049 IEA cell cycle
GO:0007252 IMP I-kappaB phosphorylation
GO:0008285 ISS negative regulation of cell proliferation
GO:0010596 IMP negative regulation of endothelial cell migration
GO:0010633 ISS negative regulation of epithelial cell migration
GO:0010719 ISS negative regulation of epithelial to mesenchymal transition
GO:0010976 IMP positive regulation of neuron projection development
GO:0014067 ISS negative regulation of phosphatidylinositol 3-kinase signaling
GO:0016525 IMP negative regulation of angiogenesis
GO:0017124 ISS SH3 domain binding
GO:0021814 IMP cell motility involved in cerebral cortex radial glia guided migration
GO:0021819 IMP layer formation in cerebral cortex
GO:0030139 ISS endocytic vesicle
GO:0030424 IDA axon
GO:0030948 IMP negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031235 IBA intrinsic component of the cytoplasmic side of the plasma membrane
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0032266 ISS phosphatidylinositol-3-phosphate binding
GO:0032312 IMP regulation of ARF GTPase activity
GO:0032320 IBA positive regulation of Ras GTPase activity
GO:0032403 ISS protein complex binding
GO:0032809 IDA neuronal cell body membrane
GO:0034144 ISS negative regulation of toll-like receptor 4 signaling pathway
GO:0034260 IMP negative regulation of GTPase activity
GO:0034261 ISS negative regulation of Ras GTPase activity
GO:0035148 IMP tube formation
GO:0035414 IMP negative regulation of catenin import into nucleus
GO:0035924 IDA cellular response to vascular endothelial growth factor stimulus
GO:0036312 ISS phosphatidylinositol 3-kinase regulatory subunit binding
GO:0036324 IMP vascular endothelial growth factor receptor-2 signaling pathway
GO:0043025 IDA neuronal cell body
GO:0043065 IMP positive regulation of apoptotic process
GO:0043122 IMP regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043124 ISS negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043254 IMP regulation of protein complex assembly
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0043410 ISS positive regulation of MAPK cascade
GO:0043507 IMP positive regulation of JUN kinase activity
GO:0043548 ISS phosphatidylinositol 3-kinase binding
GO:0043553 ISS negative regulation of phosphatidylinositol 3-kinase activity
GO:0044257 ISS cellular protein catabolic process
GO:0044300 IDA cerebellar mossy fiber
GO:0044301 IDA climbing fiber
GO:0045087 IEA innate immune response
GO:0045732 IMP positive regulation of protein catabolic process
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046330 ISS positive regulation of JNK cascade
GO:0046580 IBA negative regulation of Ras protein signal transduction
GO:0048147 IMP negative regulation of fibroblast proliferation
GO:0048812 IMP neuron projection morphogenesis
GO:0050679 ISS positive regulation of epithelial cell proliferation
GO:0050680 ISS negative regulation of epithelial cell proliferation
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070273 ISS phosphatidylinositol-4-phosphate binding
GO:0070317 ISS negative regulation of G0 to G1 transition
GO:0070373 ISS negative regulation of ERK1 and ERK2 cascade
GO:0071158 ISS positive regulation of cell cycle arrest
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071347 IDA cellular response to interleukin-1
GO:0071356 IMP cellular response to tumor necrosis factor
GO:0071901 IMP negative regulation of protein serine/threonine kinase activity
GO:0071902 IMP positive regulation of protein serine/threonine kinase activity
GO:0090129 IMP positive regulation of synapse maturation
GO:1900006 IMP positive regulation of dendrite development
GO:1900744 IMP regulation of p38MAPK cascade
GO:1900747 IDA negative regulation of vascular endothelial growth factor signaling pathway
GO:1901800 ISS positive regulation of proteasomal protein catabolic process
GO:1990032 IDA parallel fiber
GO:2000599 ISS negative regulation of cyclin catabolic process
GO:2001224 IMP positive regulation of neuron migration
GO:2001235 ISS positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000259371 DAB2IP-201 protein_coding Homo_sapiens 0 4905
ENST00000309989 DAB2IP-004 protein_coding Homo_sapiens 0 4006
ENST00000367649 RASAL2-002 protein_coding Homo_sapiens 0 416
ENST00000373782 DAB2IP-010 protein_coding Homo_sapiens 0 4540
ENST00000394340 DAB2IP-001 protein_coding Homo_sapiens 0 1393
ENST00000408936 DAB2IP-009 protein_coding Homo_sapiens 0 4353
ENST00000433130 RASAL2-003 protein_coding Homo_sapiens 0 196
ENST00000436835 DAB2IP-005 protein_coding Homo_sapiens 0 911
ENST00000459906 DAB2IP-008 processed_transcript Homo_sapiens 0 577
ENST00000462775 RASAL2-001 protein_coding Homo_sapiens 0 412

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