C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transcription factor 7-like 1 (T-cell specific, HMG-box)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000282111 TCF7L1-001 ENSG00000152284 9606 + 2:85133410-85310388 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000282111
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000282111 27.316±0.00 16.069±0.00 1.259±1.24 10.468±10.32 12.111±12.01 2.709±2.64 6.444±0.00 2.268±2.05 6.837±6.56 3.479±3.00 18.051±13.91 5.819±0.57 14.300±10.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AX CIL_0009AX_0001 VISTA 2:84977509-85579132

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 NAS DNA binding
GO:0003682 IBA chromatin binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 NAS nucleus
GO:0005667 IBA transcription factor complex
GO:0006325 NAS chromatin organization
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0007420 IBA brain development
GO:0008013 IBA beta-catenin binding
GO:0008595 IEA anterior/posterior axis specification, embryo
GO:0030111 NAS regulation of Wnt signaling pathway
GO:0035019 IEA somatic stem cell maintenance
GO:0043565 IBA sequence-specific DNA binding
GO:0043588 IEA skin development
GO:0044212 IBA transcription regulatory region DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046022 IEA positive regulation of transcription from RNA polymerase II promoter during mitosis
GO:0048319 IEA axial mesoderm morphogenesis
GO:0048699 IBA generation of neurons
GO:0048863 IEA stem cell differentiation
GO:0060070 IBA canonical Wnt signaling pathway
GO:2000036 IEA regulation of stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000069536 Tcf7l1-001 protein_coding Mus_musculus 0 2551
ENSMUST00000114053 Tcf7l1-003 protein_coding Mus_musculus 0 1604
ENSMUST00000149446 Tcf7l1-006 protein_coding Mus_musculus 0 516
ENSMUST00000141743 Tcf7l1-002 processed_transcript Mus_musculus 0 333
ENSMUST00000182651 Tcf7l1-005 processed_transcript Mus_musculus 9e-28 130
ENSMUST00000081929 Gm15401-003 protein_coding Mus_musculus 0.0000000005 71

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