C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin 1 receptor antagonist
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000114482 Il1rn-002 ENSMUSG00000026981 10090 + 2:24345310-24350936 protein_coding

Mus musculus EnsemblGRCm38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000114482
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000114482 0.754±0.37 0.071±0.03 1.173±0.01 0.033±0.02 0.870±0.32 13.831±3.61 0.062±0.06 0.150±0.10 2.915±2.72 5.472±1.52 0.058±0.03 0.693±0.33 1.095±0.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000190 CIL_000190_0002 CGP 2:24291196-24351494
CIL_000191 CIL_000191_0002 CGP 2:24336853-24409182

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001660 IEA fever generation
GO:0001960 IEA negative regulation of cytokine-mediated signaling pathway
GO:0002439 IEA chronic inflammatory response to antigenic stimulus
GO:0005149 IEA interleukin-1 receptor binding
GO:0005150 IEA interleukin-1, Type I receptor binding
GO:0005151 IEA interleukin-1, Type II receptor binding
GO:0005152 IEA interleukin-1 receptor antagonist activity
GO:0005576 IDA extracellular region
GO:0005737 IEA cytoplasm
GO:0006629 IMP lipid metabolic process
GO:0006953 IEA acute-phase response
GO:0007565 IEA female pregnancy
GO:0007613 IEA memory
GO:0010243 IEA response to organonitrogen compound
GO:0014050 IEA negative regulation of glutamate secretion
GO:0014070 IEA response to organic cyclic compound
GO:0014823 IEA response to activity
GO:0019233 IEA sensory perception of pain
GO:0019752 IEA carboxylic acid metabolic process
GO:0030073 IMP insulin secretion
GO:0030336 IEA negative regulation of cell migration
GO:0031982 IDA vesicle
GO:0032496 IEA response to lipopolysaccharide
GO:0034115 IEA negative regulation of heterotypic cell-cell adhesion
GO:0042493 IEA response to drug
GO:0042594 IEA response to starvation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045352 IEA interleukin-1 Type I receptor antagonist activity
GO:0045353 IEA interleukin-1 Type II receptor antagonist activity
GO:0045837 IEA negative regulation of membrane potential
GO:0051384 IEA response to glucocorticoid
GO:0070062 IEA extracellular vesicular exosome
GO:0070555 IEA response to interleukin-1
GO:0070670 IEA response to interleukin-4
GO:0071874 IEA cellular response to norepinephrine stimulus
GO:2000660 IEA negative regulation of interleukin-1-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000259206 IL1RN-001 protein_coding Homo_sapiens 0 412
ENST00000354115 IL1RN-002 protein_coding Homo_sapiens 0 412
ENST00000361779 IL1RN-003 protein_coding Homo_sapiens 0 412
ENST00000409052 IL1RN-004 protein_coding Homo_sapiens 0 412
ENST00000409930 IL1RN-005 protein_coding Homo_sapiens 0 455
ENST00000472292 IL1RN-009 retained_intron Homo_sapiens 2.8026e-45 185
ENST00000486167 IL1RN-008 retained_intron Homo_sapiens 2e-32 143

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