C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: optineurin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000114996 Optn-001 ENSMUSG00000026672 10090 - 2:5020642-5064045 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000114996
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000114996 3.699±1.79 10.386±1.17 3.508±0.36 3.310±2.43 2.375±0.67 6.409±1.23 5.031±1.92 1.615±0.40 5.334±2.30 2.486±0.56 21.246±2.51 1.894±1.51 14.348±7.17 22.601±2.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000968 CIL_000968_0002 VISTA 2:4582644-5183763

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000042 IEA protein targeting to Golgi
GO:0001920 IEA negative regulation of receptor recycling
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005794 IEA Golgi apparatus
GO:0005802 ISS trans-Golgi network
GO:0006914 IEA autophagy
GO:0007030 IEA Golgi organization
GO:0008022 IEA protein C-terminus binding
GO:0016236 IEA macroautophagy
GO:0017137 IEA Rab GTPase binding
GO:0031410 IEA cytoplasmic vesicle
GO:0031593 IEA polyubiquitin binding
GO:0034613 IMP cellular protein localization
GO:0043001 IEA Golgi to plasma membrane protein transport
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050829 IEA defense response to Gram-negative bacterium
GO:0070530 IDA K63-linked polyubiquitin binding
GO:0090161 ISS Golgi ribbon formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263036 OPTN-006 protein_coding Homo_sapiens 0 996
ENST00000378747 OPTN-008 protein_coding Homo_sapiens 0 1007
ENST00000378748 OPTN-005 protein_coding Homo_sapiens 0 1007
ENST00000378752 OPTN-004 protein_coding Homo_sapiens 0 1051
ENST00000378757 OPTN-007 protein_coding Homo_sapiens 0 1007
ENST00000378764 OPTN-009 protein_coding Homo_sapiens 0 1051

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