C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adrenergic receptor, beta 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000117565 Adrb3-002 ENSMUSG00000031489 10090 - 8:27226799-27228494 protein_coding

Mus musculus EnsemblGRCm38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000117565
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000117565 196.162±101.29 142.479±75.48 0.135±0.05 317.974±11.63 4.793±1.13 5.062±3.63 10.742±3.08 0.735±0.99 19.943±5.96 0.076±0.00 34.605±8.44 1.340±1.07 0.106±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009C5 CIL_0009C5_0002 VISTA 8:26806327-27408431
CIL_0007QT CIL_0007QT_0002 VISTA 8:26806345-27408424
CIL_00009T CIL_00009T_0002 CGP 8:27197460-27229588
CIL_0002IS CIL_0002IS_0002 CGP 8:27225776-27275656

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002024 IGI diet induced thermogenesis
GO:0002025 IDA vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0004939 ISS beta-adrenergic receptor activity
GO:0005886 IEA plasma membrane
GO:0007189 IDA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 ISS activation of adenylate cyclase activity
GO:0009409 IGI response to cold
GO:0015052 ISS beta3-adrenergic receptor activity
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0031649 IGI heat generation
GO:0031699 IDA beta-3 adrenergic receptor binding
GO:0040015 IGI negative regulation of multicellular organism growth
GO:0042803 ISS protein homodimerization activity
GO:0043235 ISS receptor complex
GO:0043410 ISS positive regulation of MAPK cascade
GO:0050873 IGI brown fat cell differentiation
GO:0051380 ISS norepinephrine binding
GO:0071875 IEA adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000345060 ADRB3-001 protein_coding Homo_sapiens 0 1044
ENST00000369295 ADRB1-001 protein_coding Homo_sapiens 4e-21 108
ENST00000520341 ADRB3-003 processed_transcript Homo_sapiens 0 366
ENST00000614635 ADRB3-201 protein_coding Homo_sapiens 0 1044

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